3.5.1.18: succinyl-diaminopimelate desuccinylase

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For detailed information about succinyl-diaminopimelate desuccinylase, go to the full flat file.

Reaction

Synonyms

Cgl1109, DapE, dapE-encoded N-succinyl-LL-diaminopimelic acid desuccinylase, HiDapE, N-succinyl-L,L-diaminopimelic acid desuccinylase, N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase, Rv1202, S-DAP deacylase, SDAP, sDap desuccinylase, succinyl-diaminopimelate desuccinylase, succinyldiaminopimelate desuccinylase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.18 succinyl-diaminopimelate desuccinylase

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Results	in table
26235	AA Sequence
4	Application
1	CAS Registry Number
13	Cloned(Commentary)
8	Crystallization (Commentary)
17	General Information
15	IC50 Value
31	Inhibitors
3	kcat/KM [mM/s]
9	Ki Value [mM]
24	KM Value [mM]
29	Metals/Ions
14	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
49	Organism
6	Pathway
22	PDB ID
9	pH Optimum
3	pH Range
1	pH Stability
17	Protein Variants
11	Purification (Commentary)
3	Reaction
1	Reaction Type
41	Reference
2	Specific Activity [micromol/min/mg]
41	Substrates and Products (Substrate)
11	Subunits
48	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
13	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.5.1.18 - succinyl-diaminopimelate desuccinylase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1.62

(2-carboxyethyl)-phosphonic acid

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395

17

2-amino-6-[(2-methylpropanoyl)amino]heptanedioic acid

Haemophilus influenzae

-

pH 7.5, 25°C

733082

0.092

2-thiopheneboronic acid

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395

0.034

3-mercaptobenzoic acid

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395

0.043

4-sulfanylbutanoic acid

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395

1

aceto-hydroxamic acid

Haemophilus influenzae

-

above, pH not specified in the publication, temperature not specified in the publication

711395

0.042

D-captopril

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395

0.05

D-penicillamine

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395

1

enalapril

Haemophilus influenzae

-

above, pH not specified in the publication, temperature not specified in the publication

711395

0.0033

L-captopril

2 entries

0.0137

L-Penicillamine

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395

1

N-(benzyloxycarbonyl)hydroxylamine

Haemophilus influenzae

-

above, pH not specified in the publication, temperature not specified in the publication

711395

0.01

N-phenyl-thiourea

Haemophilus influenzae

-

above, pH not specified in the publication, temperature not specified in the publication

711395

0.107

phenylboronic acid

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395

0.0033

L-captopril

Salmonella enterica

-

pH and temperature not specified in the publication

719021

0.0033

L-captopril

Haemophilus influenzae

-

pH not specified in the publication, temperature not specified in the publication

711395