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3.5.1.124: protein deglycase

This is an abbreviated version!
For detailed information about protein deglycase, go to the full flat file.

Word Map on EC 3.5.1.124

Reaction

an N6-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine
+
H2O
=
a [protein]-L-lysine
+
Lactate

Synonyms

deglycase, DJ-1, DJ-1 deglycase, DJ-1 protein, glutathione-independent glyoxalase, glyoxalase, glyoxylase III, hchA, Hsp31, Maillard deglycase, More, PARK7, Parkinsonism-associated protein, Parkinsonism-associated protein DJ-1, PfpI, yajL, yhbO

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.124 protein deglycase

Natural Substrates Products

Natural Substrates Products on EC 3.5.1.124 - protein deglycase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-arginine + H2O
a [protein]-L-arginine + (R)-lactate
show the reaction diagram
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-cysteine + H2O
a [protein]-L-cysteine + (R)-lactate
show the reaction diagram
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H2O
a [protein]-L-lysine + (R)-lactate
show the reaction diagram
methylglyoxal + H2O
(R)-lactate
show the reaction diagram
additional information
?
-