3.5.1.123: gamma-glutamylanilide hydrolase
This is an abbreviated version!
For detailed information about gamma-glutamylanilide hydrolase, go to the full flat file.
Reaction
Synonyms
atdA2, glutamine amidotransferase-like protein
ECTree
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General Information
General Information on EC 3.5.1.123 - gamma-glutamylanilide hydrolase
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metabolism
physiological function
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the enzyme, encoded by gene atdA2, is involved in aniline oxidation as a part of the aniline degradation gene cluster, catechol is the major oxidation product from aniline, gamma-glutamate is an intermediate to catechol and a direct substrate for the dioxygenase. Acinetobacter sp. strain YAA has an aniline degradation gene cluster on the plasmid pYA1, the cluster consists of 14 genes (atdA1 to atdA5 and atdRSBCDEFGH) required for the conversion of aniline into tricarboxylic acid cycle intermediates. Putative aniline oxidation mechanism of Acinetobacter sp. YAA, pathway overview
metabolism
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the enzyme, encoded by gene atdA2, is involved in aniline oxidation as a part of the aniline degradation gene cluster, catechol is the major oxidation product from aniline, gamma-glutamate is an intermediate to catechol and a direct substrate for the dioxygenase. Acinetobacter sp. strain YAA has an aniline degradation gene cluster on the plasmid pYA1, the cluster consists of 14 genes (atdA1 to atdA5 and atdRSBCDEFGH) required for the conversion of aniline into tricarboxylic acid cycle intermediates. Putative aniline oxidation mechanism of Acinetobacter sp. YAA, pathway overview
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enzyme AtdA2 prevents gamma-glutamate accumulation that is harmful to the cell
physiological function
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enzyme AtdA2 prevents gamma-glutamate accumulation that is harmful to the cell
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