3.5.1.12: biotinidase
This is an abbreviated version!
For detailed information about biotinidase, go to the full flat file.
Word Map on EC 3.5.1.12
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3.5.1.12
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newborn
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children
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seizure
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infant
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urine
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holocarboxylase
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inborn
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child
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hearing
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acidosis
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alopecia
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phenylketonuria
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carboxylases
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biotinylation
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symptomatic
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treatable
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biotin-dependent
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ataxia
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hypotonia
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hypothyroidism
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late-onset
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rash
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galactosemia
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acidurias
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avidin
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homocystinuria
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maple
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acidemia
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medicine
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syrup
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lipoylated
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biotin-responsive
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neurocutaneous
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lethargy
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biotin-binding
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paraparesis
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biotin-deficient
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seborrheic
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hyperammonemia
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3-methylcrotonyl-coa
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diagnostics
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analysis
- 3.5.1.12
- newborn
- children
- seizure
- infant
- urine
- holocarboxylase
-
inborn
- child
-
hearing
- acidosis
- alopecia
- phenylketonuria
- carboxylases
-
biotinylation
-
symptomatic
-
treatable
-
biotin-dependent
- ataxia
- hypotonia
- hypothyroidism
-
late-onset
- rash
- galactosemia
- acidurias
- avidin
- homocystinuria
-
maple
- acidemia
- medicine
- syrup
-
lipoylated
-
biotin-responsive
-
neurocutaneous
- lethargy
-
biotin-binding
- paraparesis
-
biotin-deficient
-
seborrheic
-
hyperammonemia
- 3-methylcrotonyl-coa
- diagnostics
- analysis
Reaction
Synonyms
amidohydrolase biotinidase, biocytin hydrolyzing amidase, biotinidase, biotinyl-hydrolase, BTD, lipoamidase, lipolysine hydrolase, lipoyl-X-hydrolase
ECTree
3.5.1.12 biotinidaseAdvanced search results
results (
results (KM Value
KM Value on EC 3.5.1.12 - biotinidase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
additional information
additional information
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enzyme kinetics in liver from hepatoma patients with additional hepatitis B or hepatitis C infection, or from patients with chronic active hepatitis or cirrhosis
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0.00383
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from supernatant fraction
0.00556
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from membrane fraction
0.0167
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from membrane and supernatant fraction
0.75
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from upper labial skin, male rat
1.18
Biotinyl-6-aminoquinoline
-
pH 7.0, 37°C, enzyme from upper labial skin, female rat
1.71
Biotinyl-6-aminoquinoline
-
pH 7.0, 37°C, enzyme from bone marrow, male rat
1.82
Biotinyl-6-aminoquinoline
-
pH 7.0, 37°C, enzyme from lower labial skin, female rat
1.87
Biotinyl-6-aminoquinoline
-
pH 7.0, 37°C, enzyme from diaphragm, female rat
1.87
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from diaphragm, male rat
2.43
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from cerebrum, male rat
2.67
Biotinyl-6-aminoquinoline
-
pH 7.0, 37°C, enzyme from small intestine, female rat
2.97
Biotinyl-6-aminoquinoline
-
pH 7.0, 37°C, enzyme from cerebrum, female rat
3.36
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from stomach, male rat
3.69
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from lung, female rat
3.7 - 5
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from large intestine, female rat
3.87
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from pancreatic head, female rat
3.88
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from stomach (corpus), male rat
3.9
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from uterus, female rat
4.15
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from bone marrow, female rat
4.17
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from cerebellum, female rat
4.17
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from cerebellum, male rat
4.27
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from large intestine, male rat
4.39
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from cerebrum, male rat
4.39
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from pancreatic tail, female rat
4.63
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from cerebrum, female rat
4.77
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from lower labial skin, male rat
4.77
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from tigh muscle, male rat
5.41
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from spleen, female rat
5.45
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from ovary, female rat
5.81
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from small intestine (jejunum), male rat
6.17
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from testis, male rat
6.25
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from tigh muscle, female rat
6.76
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from liver, female rat
7.75
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from small intestine (duodenum), male rat
7.97
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from kidney, female rat
8.58
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from spleen, male rat
10.1
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from esophagus, female rat
10.1
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from esophagus, male rat
11
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from abdominal skin, female rat
11.6
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from stomach (pylori), female rat
11.6
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from stomach, male rat
11.9
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from abdominal skin, male rat
11.9
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from kidney, male rat
12.1
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from small intestine (ileum), male rat
19.2
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from pancreatic head, male rat
21.7
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from pancreatic tail, male rat
24.1
Biotinyl-6-aminoquinoline
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pH 7.0, 37°C, enzyme from heart, female rat
