3.5.1.115: mycothiol S-conjugate amidase
This is an abbreviated version!
For detailed information about mycothiol S-conjugate amidase, go to the full flat file.
Word Map on EC 3.5.1.115
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3.5.1.115
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tuberculosis
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actinomycetes
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deacetylase
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glcnac-ins
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mycothiol-dependent
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electrophilic
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mercapturic
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smegmatis
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amide
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monobromobimane
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n-acetylcysteine
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metalloprotein
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antimycobacterial
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cerulenin
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rifamycin
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text
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sponge
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alpha-helices
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deacetylation
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bromotyrosine
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accys
-
medicine
- 3.5.1.115
- tuberculosis
- actinomycetes
- deacetylase
-
glcnac-ins
-
mycothiol-dependent
-
electrophilic
-
mercapturic
- smegmatis
- amide
- monobromobimane
- n-acetylcysteine
- metalloprotein
-
antimycobacterial
- cerulenin
- rifamycin
-
text
-
sponge
-
alpha-helices
-
deacetylation
-
bromotyrosine
-
accys
- medicine
Reaction
Synonyms
MCA, mycothiol S-conjugate amidase, Rv1082
ECTree
3.5.1.115 mycothiol S-conjugate amidaseAdvanced search results
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results (IC50 Value
IC50 Value on EC 3.5.1.115 - mycothiol S-conjugate amidase
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IC50 VALUE [mM] 
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
2.72
(2E)-3-(3,5-difluorophenyl)-N-[2-[(4-fluorophenyl)disulfanyl]ethyl]-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.065
(2E)-3-(3-bromophenyl)-N-[2-[(2,6-dimethylphenyl)disulfanyl]ethyl]-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.09
(2E)-3-(3-bromophenyl)-N-[2-[(4-fluorophenyl)disulfanyl]ethyl]-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.037
(2E)-3-(3-chloro-4-hydroxyphenyl)-N-[2-[(4-fluorophenyl)disulfanyl]ethyl]-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.0028
(2E)-N-(5-amino-5-iminopentyl)-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.036
(2E)-N-[2-(2-amino-1H-imidazol-5-yl)ethyl]-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.45
(2E)-N-[2-[(4-aminophenyl)disulfanyl]ethyl]-3-(3,5-difluorophenyl)-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.185
(2E)-N-[2-[(4-aminophenyl)disulfanyl]ethyl]-3-(3-bromophenyl)-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.035
(2E)-N-[2-[(4-aminophenyl)disulfanyl]ethyl]-3-(3-chloro-4-hydroxyphenyl)-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.002 - 0.003
(2Z)-N-(4-amino-4-iminobutyl)-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
0.03 - 0.037
(2Z)-N-[(2-amino-1H-imidazol-5-yl)methyl]-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
0.1
(5R,10S)-N-[2-(2-amino-1H-imidazol-5-yl)ethyl]-7,9-dibromo-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-triene-3-carboxamide
0.002
(5R,10S)-N-[2-[2-amino-4-(3,5,8-trihydroxy-4-oxo-1,4-dihydroquinolin-6-yl)-1H-imidazol-5-yl]ethyl]-7,9-dibromo-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-triene-3-carboxamide
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.03
bromotyrosine oxime
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.04
halisulfate 1
Mycolicibacterium smegmatis
-
at 31°C, pH not specified in the publication
0.0028
psammaplin A
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.1
pseudoceratine
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.07
S,S-dimethyl gliotoxin
Mycobacterium tuberculosis
-
at 31°C, pH not specified in the publication
0.05
(2S,3R,26S,27S)-2,27-diamino-1,3,26-trihydroxyoctacosan-13-one
Mycolicibacterium smegmatis
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at 31°C, pH not specified in the publication
0.1
(2S,3R,26S,27S)-2,27-diamino-1,3,26-trihydroxyoctacosan-13-one
Mycobacterium tuberculosis
-
at 31°C, pH not specified in the publication
0.002
(2Z)-N-(4-amino-4-iminobutyl)-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
Mycolicibacterium smegmatis
-
at 31°C, pH not specified in the publication
0.003
(2Z)-N-(4-amino-4-iminobutyl)-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
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at 31°C, pH not specified in the publication
0.03
(2Z)-N-[(2-amino-1H-imidazol-5-yl)methyl]-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
Mycobacterium tuberculosis
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at 31°C, pH not specified in the publication
0.037
(2Z)-N-[(2-amino-1H-imidazol-5-yl)methyl]-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
Mycolicibacterium smegmatis
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at 31°C, pH not specified in the publication
0.1
(5R,10S)-N-[2-(2-amino-1H-imidazol-5-yl)ethyl]-7,9-dibromo-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-triene-3-carboxamide
Mycolicibacterium smegmatis
-
at 31°C, pH not specified in the publication
0.1
(5R,10S)-N-[2-(2-amino-1H-imidazol-5-yl)ethyl]-7,9-dibromo-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-triene-3-carboxamide
Mycobacterium tuberculosis
-
at 31°C, pH not specified in the publication
0.0001
1-pentyl-2-[10-(3-pentylpyridinium-1-yl)decyl]pyridinium
Mycolicibacterium smegmatis
-
at 31°C, pH not specified in the publication
0.0001
1-pentyl-2-[10-(3-pentylpyridinium-1-yl)decyl]pyridinium
Mycobacterium tuberculosis
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at 31°C, pH not specified in the publication
0.002
disodium 3-[(E)-2-carboxylatoethenyl]benzoate
Mycolicibacterium smegmatis
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at 31°C, pH not specified in the publication
0.003
disodium 3-[(E)-2-carboxylatoethenyl]benzoate
Mycobacterium tuberculosis
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at 31°C, pH not specified in the publication
0.0005
oceanapiside
Mycolicibacterium smegmatis
-
at 31°C, pH not specified in the publication
0.02
psammaplysin A
Mycobacterium tuberculosis
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pH and temperature not specified in the publication
0.03
psammaplysin A
Mycolicibacterium smegmatis
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at 31°C, pH not specified in the publication
0.03
psammaplysin A
Mycobacterium tuberculosis
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at 31°C, pH not specified in the publication
0.02
psammaplysin B
Mycolicibacterium smegmatis
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at 31°C, pH not specified in the publication
0.026
psammaplysin B
Mycobacterium tuberculosis
-
pH and temperature not specified in the publication
0.03
psammaplysin B
Mycobacterium tuberculosis
-
at 31°C, pH not specified in the publication
