3.5.1.114: N-acyl-aromatic-L-amino acid amidohydrolase
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Word Map on EC 3.5.1.114
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Synonyms
AA3, AAIII, Acy3, aminoacylase 3, aminoacylase III
ECTree
3.5.1.114 N-acyl-aromatic-L-amino acid amidohydrolaseAdvanced search results
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Source Tissue on EC 3.5.1.114 - N-acyl-aromatic-L-amino acid amidohydrolase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
AA3 expression in the hepatocellular carcinoma cell lines is 5 to 20 times greater than in normal primary hepatocytes
AA3 expression in the hepatocellular carcinoma cell lines is 5 to 20 times greater than in normal primary hepatocytes
the enzyme is expressed predominantly in kidney, localized predominantly to the apical domain of S1 proximal tubules and the cytoplasm of S2 and S3 proximal tubules. The data suggest that in kidney proximal tubules, aminoacylase III plays an important role in deacetylating mercapturic acids
