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3.5.1.114: N-acyl-aromatic-L-amino acid amidohydrolase

This is an abbreviated version!
For detailed information about N-acyl-aromatic-L-amino acid amidohydrolase, go to the full flat file.

Word Map on EC 3.5.1.114

Reaction

an N-acetyl-L-cysteine-S-conjugate
+
H2O
=
an L-cysteine-S-conjugate
+
acetate

Synonyms

AA3, AAIII, Acy3, aminoacylase 3, aminoacylase III

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.114 N-acyl-aromatic-L-amino acid amidohydrolase

KM Value

KM Value on EC 3.5.1.114 - N-acyl-aromatic-L-amino acid amidohydrolase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.2 - 0.53
4-hydroxy-2-nonenal mercapturate
0.71 - 0.82
acrolein mercapturate
1.11 - 17.73
N-acetyl-1,2-dichlorovinyl-L-cysteine
1.8
N-acetyl-L-histidine
1.3
N-acetyl-L-lysine
-
pH 7.5, 37°C
1.6
N-acetyl-L-phenylalanine
1.2
N-acetyl-L-tryptophan
-
pH 7.5, 37°C
0.18 - 5.2
N-acetyl-L-tyrosine
0.25
N-acetyl-S-(1,1,2,2-tetrafluoroethyl)-L-cysteine
-
pH 7.5, 37°C
1.2
N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine
-
pH 7.5, 37°C
1
N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine
-
pH 7.5, 37°C
0.56 - 1.3
N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine
5.3
N-acetyl-S-(2,2-dichloro-1,1-difluoroethyl)-L-cysteine
-
pH 7.5, 37°C
0.4
N-acetyl-S-(2,2-dichlorovinyl)-L-cysteine
-
pH 7.5, 37°C
0.3
N-acetyl-S-(2,2-difluoro-1,1-dichloroethyl)-L-cysteine
-
pH 7.5, 37°C
0.28
N-acetyl-S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine
-
pH 7.5, 37°C
1.45
N-acetyl-S-(2-chlorobenzyl)-L-cysteine
-
pH 7.5, 37°C
1.3
N-acetyl-S-(2-fluorobenzyl)-L-cysteine
-
pH 7.5, 37°C
0.6
N-acetyl-S-(3-fluorobenzyl)-L-cysteine
-
pH 7.5, 37°C
0.5
N-acetyl-S-(4-bromobenzyl)-L-cysteine
-
pH 7.5, 37°C
0.3
N-acetyl-S-(4-chlorobenzyl)-L-cysteine
-
pH 7.5, 37°C
0.8
N-acetyl-S-(4-methoxybenzyl)-L-cysteine
-
pH 7.5, 37°C
1.1
N-acetyl-S-benzyl-L-cysteine
0.14
N-acetyl-S-geranylgeranyl-L-cysteine
pH 7.5, 37°C
0.025
N-acetyl-S-[(2E,6E)-farnesyl]-L-cysteine
pH 7.5, 37°C
additional information
additional information
Michaelis-Menten kinetics
-