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3.5.1.114: N-acyl-aromatic-L-amino acid amidohydrolase

This is an abbreviated version!
For detailed information about N-acyl-aromatic-L-amino acid amidohydrolase, go to the full flat file.

Word Map on EC 3.5.1.114

Reaction

an N-acetyl-L-cysteine-S-conjugate
+
H2O
=
an L-cysteine-S-conjugate
+
acetate

Synonyms

AA3, AAIII, Acy3, aminoacylase 3, aminoacylase III

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.114 N-acyl-aromatic-L-amino acid amidohydrolase

IC50 Value

IC50 Value on EC 3.5.1.114 - N-acyl-aromatic-L-amino acid amidohydrolase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.063
2-((E)-[(4H-1,2,4-triazol-4-yl)imino]methyl)-1-benzothiophene-3-ol
Rattus norvegicus
pH and temperature not specified in the publication
0.00000063
2-(4-ethoxyphenyl)-2-methylsuccinic acid
Rattus norvegicus
pH and temperature not specified in the publication
0.000079
2-([(3-fluoro-4-methoxyphenyl)methyl]sulfanyl)-1-methyl-1H-benzimidazole-5-sulfonamide
Rattus norvegicus
pH and temperature not specified in the publication
0.00004
2-([2-chloro-4-(thiocyanato)phenyl]carbamoyl)benzoic acid
Rattus norvegicus
pH and temperature not specified in the publication
0.0016
2-[(1,3-benzothiazol-2-yl)sulfanyl]ethan-1-amine
Rattus norvegicus
pH and temperature not specified in the publication
0.0101
clioquinol
Rattus norvegicus
pH and temperature not specified in the publication
10
ebselen
Rattus norvegicus
pH and temperature not specified in the publication
0.0000032
N-(2,3,5-trichloro-4-oxocyclohexa-2,5-dien-1-ylidene)benzenesulfonamide
Rattus norvegicus
pH and temperature not specified in the publication