3.5.1.114: N-acyl-aromatic-L-amino acid amidohydrolase

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For detailed information about N-acyl-aromatic-L-amino acid amidohydrolase, go to the full flat file.

Reaction

Synonyms

AA3, AAIII, Acy3, aminoacylase 3, aminoacylase III

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.114 N-acyl-aromatic-L-amino acid amidohydrolase

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Results	in table
14	AA Sequence
1	Application
8	Cloned(Commentary)
1	Crystallization (Commentary)
4	Disease/ Diagnostics
1	Expression
11	General Information
8	IC50 Value
19	Inhibitors
8	kcat/KM [mM/s]
77	KM Value [mM]
2	Localization
9	Metals/Ions
5	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
10	Organism
6	pH Optimum
1	Posttranslational Modification
7	Protein Variants
7	Purification (Commentary)
2	Reaction
10	Reference
35	Source Tissue
44	Substrates and Products (Substrate)
4	Subunits
17	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
10	Turnover Number [1/s]

Engineering

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Engineering on EC 3.5.1.114 - N-acyl-aromatic-L-amino acid amidohydrolase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

D68A

Mus musculus

Q91XE4

inactive mutant enzyme

711284

E177A

Mus musculus

Q91XE4

inactive mutant enzyme

711284

E24A

Mus musculus

Q91XE4

inactive mutant enzyme

711284

H116A

Mus musculus

Q91XE4

inactive mutant enzyme

711284

H21A

Mus musculus

Q91XE4

inactive mutant enzyme

711284

R63A

Mus musculus

Q91XE4

inactive mutant enzyme

711284

Y287A

Mus musculus

Q91XE4

inactive mutant enzyme

711284