3.5.1.11: penicillin amidase

This is an abbreviated version!
For detailed information about penicillin amidase, go to the full flat file.

Word Map on EC 3.5.1.11

3.5.1.11

6-aminopenicillanic

phenylacetic

biocatalyst

anandamide

acylases

cannabinoids

cephalosporin

synthesis

binuclear

alcaligenes

cephalexin

megaterium

endocannabinoids

semi-synthetic

3.5.1.1

kluyvera

l-asparagine

dihydroorotase

phenylacetylated

allantoinase

dihydropyrimidinase

lactonase

amoxicillin

rettgeri

eupergit

multipoint

acyl-enzyme

asparaginase

hydantoinase

phenoxyacetic

aminoacylase

7-aminocephalosporanic

phosphotriesterase

sphaericus

hydantoin

providencia

n-acylethanolamines

penicillanic

dihydrouracil

cleas

pharmacology

industry

Reaction

Synonyms

ACPGA001 PGA, AfPGA, alpha-acylamino-beta-lactam acylhydrolase, amidase, amidohydrolase, ampicillin acylase, AuAAC, benzylpenicillin acylase, BmPGA, Eca3205, KcPGA, maPGA, More, novozym 217, PA, PAC, penicillin acylase, penicillin amidase, Penicillin amidohydrolase, penicillin G acylase, Penicillin G amidase, Penicillin G amidohydrolase, penicillin V acylase, Penicillin V amidase, penicillin-G acylase, PGA, PGA650, PVA, semacylase, Sm-PVA, YxeI

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.1 In linear amides

3.5.1.11 penicillin amidase

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Results	in table
18	Activating Compound
1369	AA Sequence
46	Application
1	CAS Registry Number
48	Cloned(Commentary)
10	Crystallization (Commentary)
1	Expression
10	General Information
9	General Stability
86	Inhibitors
71	kcat/KM [mM/s]
43	Ki Value [mM]
187	KM Value [mM]
46	Localization
7	Metals/Ions
53	Molecular Weight [Da]
48	Natural Substrates/ Products (Substrates)
8	Organic Solvent Stability
210	Organism
2	Pathway
109	PDB ID
58	pH Optimum
23	pH Range
23	pH Stability
15	pI Value
19	Posttranslational Modification
194	Protein Variants
57	Purification (Commentary)
3	Reaction
2	Reaction Type
202	Reference
2	Renatured (Commentary)
10	Source Tissue
71	Specific Activity [micromol/min/mg]
8	Storage Stability
448	Substrates and Products (Substrate)
45	Subunits
171	Synonyms
1	Systematic Name
51	Temperature Optimum [°C]
17	Temperature Range [°C]
57	Temperature Stability [°C]
149	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.5.1.11 - penicillin amidase

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benzylpenicillin + H2O

phenylacetic acid + 6-aminopenicillanate

3 entries

penicillin + H2O

a carboxylate + 6-aminopenicillanate

Priestia megaterium

Q60136

679882

penicillin dihydroF + H2O

Streptomyces lavendulae

substrate of immobilized enzyme

711057

penicillin F + H2O

Streptomyces lavendulae

substrate of immobilized enzyme

711057

penicillin G + H2O

6-aminopenicillanic acid + phenyl acetic acid

2 entries

penicillin G + H2O

6-aminopenicillanic acid + phenylacetic acid

5 entries

penicillin G + H2O

phenylacetate + 6-aminopenicillanate

7 entries

penicillin G + H2O

phenylacetic acid + 6-aminopenicillanate

9 entries

penicillin K + H2O

Streptomyces lavendulae

substrate of immobilized enzyme

711057

penicillin K + H2O

octanoic acid + 6-aminopenicillanate

Thermus thermophilus

Q72G76

733165

penicillin V + H2O

6-aminopenicillanic acid + phenoxyacetic acid

Streptomyces lavendulae

substrate of soluble and immobilized enzyme

711057

penicillin V + H2O

phenoxyacetate + 6-aminopenicillinate

Buckleyzyma aurantiaca

712854

penicillin V + H2O

phenoxyacetic acid + 6-aminopenicillanate

Priestia megaterium

678562

additional information

5 entries