3.5.1.104: peptidoglycan-N-acetylglucosamine deacetylase

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For detailed information about peptidoglycan-N-acetylglucosamine deacetylase, go to the full flat file.

Reaction

Synonyms

BA1961, BA1977, BA2944, BC1960, Bc1974, BC3618, BC_1960, BC_1974, enzyme BC1960, enzyme BC3618, GlcNAc deacetylase, HP0310, HP310, HpPgdA, Lmo0415, MurNAc deacetylase, N-acetylglucosamine deacetylase, N-acetylglucosamine deacetylase BC1960, PdaC, peptidoglycan deacetlyase, peptidoglycan deacetylase, peptidoglycan GlcNAc deacetylase, peptidoglycan GlcNAc deacetylases, peptidoglycan N-acetylglucosamine deacetylase, peptidoglycan N-acetylglucosamine deacetylase BC1960, PG N-deacetylase, Pgd, pgdA, pgdA_1, pgdA_2, PGNG-dac, PGNGdacs, polysaccharide deacetylase, polysaccharide deacetylase C, Rv1096 protein, SfPgdA, SpPgdA, yheN, YjeA

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.104 peptidoglycan-N-acetylglucosamine deacetylase

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Results	in table
818	AA Sequence
3	Application
1	CAS Registry Number
17	Cloned(Commentary)
10	Crystallization (Commentary)
6	Expression
52	General Information
4	IC50 Value
41	Inhibitors
4	kcat/KM [mM/s]
4	Ki Value [mM]
21	KM Value [mM]
9	Localization
20	Metals/Ions
1	Molecular Weight [Da]
22	Natural Substrates/ Products (Substrates)
161	Organism
8	pH Optimum
13	Protein Variants
6	Purification (Commentary)
1	Reaction
40	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
65	Substrates and Products (Substrate)
9	Subunits
126	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Stability [°C]
11	Turnover Number [1/s]

Expression

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Expression on EC 3.5.1.104 - peptidoglycan-N-acetylglucosamine deacetylase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

expression of the pgdA gene is increased upon interaction of the bacterium with neutrophils in vitro as well as in vivo in experimentally inoculated mice

Streptococcus suis

-

700275

HP310 is markedly up-expressed upon cell exposure to oxidative stress

Helicobacter pylori

-

698982

PgdA is highly expressed under oxidative stress

2 entries

SfPgdA expression is controlled by PhoP, a phoP mutant does not produce SfPgdA, which results in increased sensitivity to lysozyyme

Shigella flexneri

-

720379

SfPgdA expression is enhanced under low magnesium concentration

Shigella flexneri

-

720379

PgdA is highly expressed under oxidative stress

Helicobacter pylori

O25080

729936

PgdA is highly expressed under oxidative stress

Helicobacter pylori ATCC 700392

-

-