3.5.1.103: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase

This is an abbreviated version!
For detailed information about N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase, go to the full flat file.

Reaction

Synonyms

1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, 1-D-myo-inosityl 2-N-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, AcGI deacetylase, GlcNAc-Ins deacetylase, GlcNAc-Ins-deacetylase, MshB, N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase, N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-D-glucopyranoside deacetylase, N-acetyl-1-D-myo-inosityl-2-deoxy-alpha-D-glucopyranoside deacetylase, N-acetylglucosaminylinositol-deacetylase, Rv1170

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.103 N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase

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Results	in table
1	Activating Compound
3608	AA Sequence
4	Application
1	CAS Registry Number
8	Cloned(Commentary)
7	Crystallization (Commentary)
10	General Information
14	Inhibitors
22	kcat/KM [mM/s]
25	KM Value [mM]
21	Metals/Ions
9	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
68	Organism
1	Pathway
2	PDB ID
3	pH Optimum
22	Protein Variants
5	Purification (Commentary)
5	Reaction
25	Reference
1	Specific Activity [micromol/min/mg]
54	Substrates and Products (Substrate)
11	Subunits
48	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
24	Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.24 - 0.49

1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol

2 entries

0.0048 - 2.1

N-acetyl-D-glucosamine

20 entries

0.49

N-deacetyl-N-formylmycothiol-monobromobimane conjugate

Mycobacterium tuberculosis

P9WJN3

pH 7.4, 37°C

701051

0.12

phenyl-2-acetamido-2-deoxy-1-thio-alpha-D-glucopyranoside

Mycobacterium tuberculosis

-

pH 7.5, 37°C

696764

0.24

1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol

Mycobacterium tuberculosis

-

pH 7.5, 37°C

696764

0.49

1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol

Mycobacterium tuberculosis

P9WJN3

pH 7.5, 37°C

701051

0.0048

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

mutant D15A, pH 7.5, 30°C

720006

0.0048

N-acetyl-D-glucosamine

Mycobacterium tuberculosis

P9WJN3

pH 7.5, 30°C, mutant enzyme D15A

752756

0.0095

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

mutant Y142F, pH 7.5, 30°C

720006

0.0115

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

mutant H144A, pH 7.5, 30°C

720006

0.02

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

mutant Y142Q, pH 7.5, 30°C

720006

0.03

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

mutant Y142A, pH 7.5, 30°C

720006

0.0333

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

mutant D146A, pH 7.5, 30°C

720006

0.047

N-acetyl-D-glucosamine

Mycobacterium tuberculosis

P9WJN3

pH 7.5, 30°C, mutant enzyme D146N

752756

0.11

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

Fe3+-enzyme, pH 7.5, 30°C

719933

0.13

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

apo-enzyme, pH 7.5, 30°C

719933

0.27

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

Ni2+-enzyme, pH 7.5, 30°C

719933

0.33

N-acetyl-D-glucosamine

Mycobacterium tuberculosis

P9WJN3

pH 7.5, 30°C, mutant enzyme M98A

752756

0.38

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

Mn2+-enzyme, pH 7.5, 30°C

719933

0.6

N-acetyl-D-glucosamine

Mycobacterium tuberculosis

P9WJN3

pH 7.5, 30°C, mutant enzyme F216A

752756

0.72

N-acetyl-D-glucosamine

Mycobacterium tuberculosis

P9WJN3

pH 7.5, 30°C, mutant enzyme L19A

752756

0.77

N-acetyl-D-glucosamine

Mycobacterium tuberculosis

P9WJN3

pH 7.5, 30°C, wild-type enzyme

752756

0.77

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

wild-type, pH 7.5, 30°C

720006

1.05

N-acetyl-D-glucosamine

Mycobacterium tuberculosis

P9WJN3

pH 7.5, 30°C, mutant enzyme E47A

752756

1.1

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

Co2+-enzyme, pH 7.5, 30°C

719933

2.1

N-acetyl-D-glucosamine

Mycolicibacterium smegmatis

-

Fe2+-enzyme, pH 7.5, 30°C

719933