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3.5.1.101: L-proline amide hydrolase

This is an abbreviated version!
For detailed information about L-proline amide hydrolase, go to the full flat file.

Reaction

(S)-piperidine-2-carboxamide
+
H2O
=
(S)-piperidine-2-carboxylate
+
NH3

Synonyms

L-amino acid amidase, LaaA, S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.101 L-proline amide hydrolase

Inhibitors

Inhibitors on EC 3.5.1.101 - L-proline amide hydrolase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ag+
1 mM, complete inhibition
Cd2+
1 mM, complete inhibition
CoCl2
1 mM, 52% inhibition
Hg2+
1 mM, complete inhibition
iodoacetate
1 mM, 40% inhibition
NEM
1 mM, 24% inhibition
NiCl2
1 mM, 70% inhibition
p-chloromercuribenzoate
1 mM, 67% inhibition
PbCl2
1 mM, 73% inhibition
phenylhydrazine
1 mM, complete inhibition
Zn2+
1 mM, complete inhibition