3.5.1.10: formyltetrahydrofolate deformylase

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For detailed information about formyltetrahydrofolate deformylase, go to the full flat file.

Reaction

Synonyms

10-formyltetrahydrofolate hydrolase, Formyl-FH(4) hydrolase, formyl-FH4 hydrolase, formyltetrahydrofolate hydrolase, FTH

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.10 formyltetrahydrofolate deformylase

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Results	in table
1	Activating Compound
24218	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
1	Inhibitors
5	KM Value [mM]
3	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
6	Organism
9	Pathway
10	PDB ID
9	Protein Variants
1	Purification (Commentary)
3	Reaction
2	Reaction Type
6	Reference
1	Specific Activity [micromol/min/mg]
3	Substrates and Products (Substrate)
1	Subunits
5	Synonyms
1	Systematic Name

Engineering

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Engineering on EC 3.5.1.10 - formyltetrahydrofolate deformylase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

H100A

Rattus norvegicus

-

soluble, shows enzymic activity

392346

H106A

Rattus norvegicus

-

insoluble, no enzymatic activity

392346

H106E

Rattus norvegicus

-

insoluble, no enzymatic activity

392346

H106K

Rattus norvegicus

-

insoluble, no enzymatic activity

392346

H106N

Rattus norvegicus

-

insoluble, no enzymatic activity

392346

H106Q

Rattus norvegicus

-

insoluble, no enzymatic activity

392346

H106R

Rattus norvegicus

-

insoluble, no enzymatic activity

392346

H113A

Rattus norvegicus

-

insoluble, shows enzymic activity

392346

H125A

Rattus norvegicus

-

soluble, shows enzymic activity

392346