3.4.24.B8: ADAM1 endopeptidase

This is an abbreviated version!
For detailed information about ADAM1 endopeptidase, go to the full flat file.

Reaction

proteolytic degradation of proteins =

Synonyms

a disintegrin and metalloprotease 1, a disintegrin and metalloproteinase domain 1, a disintegrin and metalloproteinase domain 1a, a disintegrin and metalloproteinase domain 1b, ADAM 1, ADAM 1a, ADAM 1b, ADAM-1, ADAM1, ADAM1a, ADAM1b, fertilin, fertilin alpha, fertilin alpha 1a subunit, fertilin alpha 1b subunit, fertilin alpha subunit, M12.201, PH-30

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.B8 ADAM1 endopeptidase

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Results	in table
4	AA Sequence
2	Application
1	CAS Registry Number
2	Cloned(Commentary)
28	Disease/ Diagnostics
1	General Information
1	Inhibitors
8	Localization
5	Metals/Ions
9	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
11	Organism
6	Posttranslational Modification
2	Protein Variants
1	Purification (Commentary)
3	Reaction
6	Reaction Type
10	Reference
13	Source Tissue
10	Substrates and Products (Substrate)
8	Subunits
29	Synonyms

Molecular Weight

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of the Enzyme Summary Page.

Molecular Weight on EC 3.4.24.B8 - ADAM1 endopeptidase

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MOLECULAR WEIGHT

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

100000

2 entries

10800

Cavia porcellus

-

estimated from SDS-PAGE band pattern

682737

120000

Mus musculus

-

x * 48000, mature isozyme a, SDS-PAGE, x * 60000, mature isozyme b, SDS-PAGE, x * 100000, precursor of isozyme a, SDS-PAGE, x * 120000, precursor of isozyme b, SDS-PAGE

649618

44000

Homo sapiens

-

1 * 60000, alpha subunit, + 1 * 44000, beta subunit, SDS-PAGE

653330

48000

Mus musculus

-

x * 48000, mature isozyme a, SDS-PAGE, x * 60000, mature isozyme b, SDS-PAGE, x * 100000, precursor of isozyme a, SDS-PAGE, x * 120000, precursor of isozyme b, SDS-PAGE

649618

60000

2 entries

95000

Sus scrofa

-

unprocessed expected mass of ADAM-1

721017

100000

Sus scrofa

-

gel filtration

721017

100000

Mus musculus

-

x * 48000, mature isozyme a, SDS-PAGE, x * 60000, mature isozyme b, SDS-PAGE, x * 100000, precursor of isozyme a, SDS-PAGE, x * 120000, precursor of isozyme b, SDS-PAGE

649618

60000

Homo sapiens

-

1 * 60000, alpha subunit, + 1 * 44000, beta subunit, SDS-PAGE

653330

60000

Mus musculus

-

x * 48000, mature isozyme a, SDS-PAGE, x * 60000, mature isozyme b, SDS-PAGE, x * 100000, precursor of isozyme a, SDS-PAGE, x * 120000, precursor of isozyme b, SDS-PAGE

649618