3.4.24.B8: ADAM1 endopeptidase
This is an abbreviated version!
For detailed information about ADAM1 endopeptidase, go to the full flat file.
Reaction
proteolytic degradation of proteins =
Synonyms
a disintegrin and metalloprotease 1, a disintegrin and metalloproteinase domain 1, a disintegrin and metalloproteinase domain 1a, a disintegrin and metalloproteinase domain 1b, ADAM 1, ADAM 1a, ADAM 1b, ADAM-1, ADAM1, ADAM1a, ADAM1b, fertilin, fertilin alpha, fertilin alpha 1a subunit, fertilin alpha 1b subunit, fertilin alpha subunit, M12.201, PH-30
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Engineering
Engineering on EC 3.4.24.B8 - ADAM1 endopeptidase
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additional information
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ADAM1a-deficient mice, capable of fertilizing cumulus-intact, zona pellucida-intact eggs in vitro
additional information
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ADAM1b deficient mice, no significant defect in sperm functions such as migration from the uterus into oviduct, binding to egg zona pellucida, and fusion with zona pellucida-free eggs, but severe reduction of ADAM2 on cell surface