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3.4.24.B6: matrix metalloproteinase-20

This is an abbreviated version!
For detailed information about matrix metalloproteinase-20, go to the full flat file.

Word Map on EC 3.4.24.B6

Reaction

proteolytic cleavage of ameloblastin =

Synonyms

enamel metalloproteinase, enamel protease, enamelysin, M10.019, matrix metalloproteinase 20, MMP-20, MMP20

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B6 matrix metalloproteinase-20

Inhibitors

Inhibitors on EC 3.4.24.B6 - matrix metalloproteinase-20

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
hydroxyapatite
-
-
marimastat
-
alters morphogenesis and mineralization of the tooth germs associated with inhibition of activation of MMP-20
N-isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid
-
NaF
-
0.01 mM NaF downregulates the synthesis of MMP-20 by 21%
SYGYEPMGGWLHHQ
competive against Mca-KPLGL-Dpa-AR-NH2
SYGYETMGGWLHHQ
competive against Mca-KPLGL-Dpa-AR-NH2
tissue matrix metalloprotease inhibitor TIMP-2
-
additional information
inhibitor design, determination of the features of the individual binding pockets of the enzyme
-