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3.4.24.B5: matrix metalloproteinase-15

This is an abbreviated version!
For detailed information about matrix metalloproteinase-15, go to the full flat file.

Word Map on EC 3.4.24.B5

Reaction

proteolytic degradation of proteins =

Synonyms

M10.015, matrix metalloproteinase 15, membrane type 2 matrix metalloproteinase, membrane type 2-Mmp, membrane-type matrix metalloproteinase, membrane-type matrix metalloproteinase 2, membrane-type-1 matrix metalloproteinase, membrane-type-2 matrix metalloproteinase, membrane-type-3 matrix metalloproteinase, MMP-15, MMP15, MT MMP, MT-MMP 2, MT1 MMP, MT2 MMP, MT2-MMP, Mt2-mmp/Mmp15, MT2MMP, MT3 MMP, MTMMP2, SMCP-2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B5 matrix metalloproteinase-15

Reference

topprint

Reference on EC 3.4.24.B5 - matrix metalloproteinase-15

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Mus musculus (O54732), Homo sapiens (P51511)
Manually annotated by BRENDA team
Butler, G.S.; Will, H.; Atkinson, S.J.; Murphy, G.
Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases
Eur. J. Biochem.
244
653-657
1997
Homo sapiens
Manually annotated by BRENDA team
Shofuda, K.I.; Moriyama, K.; Nishihashi, A.; Higashi, S.; Mizushima, H.; Yasumitsu, H.; Miki, K.; Sato, H.; Seiki, M.; Miyazaki, K.
Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells
J. Biochem.
124
462-470
1998
Homo sapiens
Manually annotated by BRENDA team
Belkin, A.M.; Akimov, S.S.; Zaritskaya, L.S.; Ratnikov, B.I.; Deryugina, E.I.; Strongin, A.Y.
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion
J. Biol. Chem.
276
18415-18422
2001
Homo sapiens (P50281)
Manually annotated by BRENDA team
Wallard, M.J.; Pennington, C.J.; Veerakumarasivam, A.; Burtt, G.; Mills, I.G.; Warren, A.; Leung, H.Y.; Murphy, G.; Edwards, D.R.; Neal, D.E.; Kelly, J.D.
Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma
Br. J. Cancer
94
569-577
2006
Homo sapiens
Manually annotated by BRENDA team
Jones, L.E.; Humphreys, M.J.; Campbell, F.; Neoptolemos, J.P.; Boyd, M.T.
Comprehensive analysis of matrix metalloproteinase and tissue inhibitor expression in pancreatic cancer: increased expression of matrix metalloproteinase-7 predicts poor survival
Clin. Cancer Res.
10
2832-2845
2004
Homo sapiens
Manually annotated by BRENDA team
Abraham, R.; Schaefer, J.; Rothe, M.; Bange, J.; Knyazev, P.; Ullrich, A.
Identification of MMP-15 as an anti-apoptotic factor in cancer cells
J. Biol. Chem.
280
34123-34132
2005
Homo sapiens (P51511), Homo sapiens
Manually annotated by BRENDA team
Toft-Hansen, H.; Nuttall, R.K.; Edwards, D.R.; Owens, T.
Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis
J. Immunol.
173
5209-5218
2004
Mus musculus
Manually annotated by BRENDA team
Hiden, U.; Wadsack, C.; Prutsch, N.; Gauster, M.; Weiss, U.; Frank, H.G.; Schmitz, U.; Fast-Hirsch, C.; Hengstschlaeger, M.; Poetgens, A.; Rueben, A.; Knoefler, M.; Haslinger, P.; Huppertz, B.; Bilban, M.; Kaufmann, P.; Desoye, G.
The first trimester human trophoblast cell line ACH-3P: a novel tool to study autocrine/paracrine regulatory loops of human trophoblast subpopulations - TNF-alpha stimulates MMP15 expression
BMC Dev. Biol.
7
137
2007
Homo sapiens
Manually annotated by BRENDA team
Morrison, C.J.; Overall, C.M.
TIMP independence of matrix metalloproteinase (MMP)-2 activation by membrane type 2 (MT2)-MMP is determined by contributions of both the MT2-MMP catalytic and hemopexin C domains
J. Biol. Chem.
281
26528-26539
2006
Homo sapiens
Manually annotated by BRENDA team
Kaituu-Lino, T.J.; Palmer, K.; Tuohey, L.; Ye, L.; Tong, S.
MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin
PLoS ONE
7
e39864
2012
Homo sapiens (P51511)
Manually annotated by BRENDA team
Ogiwara, K.; Takahashi, T.
Nuclear progestin receptor phosphorylation by Cdk9 is required for the expression of Mmp15, a protease indispensable for ovulation in Medaka
Cells
8
215
2019
Oryzias latipes (H2MKS4), Oryzias latipes
Manually annotated by BRENDA team
Feinberg, T.Y.; Rowe, R.G.; Saunders, T.L.; Weiss, S.J.
Functional roles of MMP14 and MMP15 in early postnatal mammary gland development
Development
143
3956-3968
2016
Mus musculus (O54732)
Manually annotated by BRENDA team
Majali-Martinez, A.; Velicky, P.; Pollheimer, J.; Knoefler, M.; Yung, H.W.; Burton, G.J.; Tabrizi-Wizsy, N.G.; Lang, U.; Hiden, U.; Desoye, G.; Dieber-Rotheneder, M.
Endothelin-1 down-regulates matrix metalloproteinase 14 and 15 expression in human first trimester trophoblasts via endothelin receptor type B
Hum. Reprod.
32
46-54
2017
Homo sapiens (P51511), Homo sapiens
Manually annotated by BRENDA team
Wu, Y.; Pan, S.; Leng, J.; Xie, T.; Jamal, M.; Yin, Q.; Li, J.; He, C.; Dong, X.; Shao, L.; Zhang, Q.
The prognostic value of matrix metalloproteinase-7 and matrix metalloproteinase-15 in acute myeloid leukemia
J. Cell. Biochem.
120
10613-10624
2019
Homo sapiens (P51511), Homo sapiens
Manually annotated by BRENDA team