3.4.24.B35: Vipera ammodytes ammodytes metalloproteinase VaH4

This is an abbreviated version, for detailed information about Vipera ammodytes ammodytes metalloproteinase VaH4, go to the full flat file.

Reaction

Cleavage of Glu422-/-Leu423 and Glu520-/-Phe521 bond of alpha-chain of human fibrinogen. Fibrinogen beta-chain is hydrolysed only partially at Lys22-/-Arg23 and Pro28-Leu29. In insulin B-chain the enzyme preferentially cleaves Tyr16-/-Leu17, followed by Gln4-/-His5 and His10-/-Leu11 =

Synonyms

hemorrhagin VaH4

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B35 Vipera ammodytes ammodytes metalloproteinase VaH4