3.4.24.B3: matrix metalloproteinase-11

This is an abbreviated version!
For detailed information about matrix metalloproteinase-11, go to the full flat file.

Word Map on EC 3.4.24.B3

3.4.24.B3

metalloproteinases

metastasis

mmp-2

timps

gelatinase

microperoxidase-11

metamorphosis

tadpole

matrilysin

menstrual

medicine

stromelysin-2

microperoxidase

collagenase-3

pharmacology

diagnostics

Reaction

proteolytic degradation of proteins =

Synonyms

M10.007, matrix metalloproteinase 11, matrix metalloproteinase-11, matrix metalloproteinase-11/stromelysin-3, matrixin, matrixin 11, MMP stromelysin-3, MMP-11, MMP-11 proteinase, MMP11, More, MP-11, SL-3, ST-3, ST3, stromelysin 3, stromelysin-3

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.B3 matrix metalloproteinase-11

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Results	in table
7	Activating Compound
6	AA Sequence
17	Application
1	CAS Registry Number
24	Cloned(Commentary)
2	Crystallization (Commentary)
1886	Disease/ Diagnostics
5	Expression
20	General Information
73	Inhibitors
53	Ki Value [mM]
12	KM Value [mM]
11	Localization
16	Metals/Ions
12	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
168	Organism
7	pH Optimum
9	Posttranslational Modification
21	Protein Variants
7	Purification (Commentary)
3	Reaction
14	Reaction Type
57	Reference
6	Renatured (Commentary)
91	Source Tissue
6	Specific Activity [micromol/min/mg]
86	Substrates and Products (Substrate)
12	Subunits
127	Synonyms
7	Temperature Optimum [°C]
16	Turnover Number [1/s]

KM Value

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KM Value on EC 3.4.24.B3 - matrix metalloproteinase-11

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0.003 - 0.088

dansyl-Pro-Leu-Ala-Leu-Trp-Ala-Arg-NH2

4 entries

0.0045 - 0.0064

dansyl-Pro-Leu-Ala-S-[(4-methoxyphenyl)methyl]Cys-Trp-Ala-Arg-NH2

3 entries

0.294 - 0.705

GGAANLVRGG

2 entries

0.148 - 0.207

GGYAELRMGG

2 entries

additional information

2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-(1-benzyl-2-oxo-2-thiazol-2-yl-ethyl)-acetamide

Mus musculus

substrate specificity with synthetic substrates

651898