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3.4.24.B27: ADAM19

This is an abbreviated version!
For detailed information about ADAM19, go to the full flat file.

Word Map on EC 3.4.24.B27

Reaction

proteolysis of proteins =

Synonyms

ADAM19, ADAM19 endopeptidase, adamalysin19, disintegrin and metalloproteinase domain-containing protein 19

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B27 ADAM19

Natural Substrates Products

Natural Substrates Products on EC 3.4.24.B27 - ADAM19

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
pro-renin receptor + H2O
fragments of pro-renin receptor
show the reaction diagram
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the pro-renin receptor is cleaved by ADAM19 in the Golgi leading to the secretion of its N-terminal fragment into extracellular space
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-
?
additional information
?
-
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ADAM19 autolysis is activated by lipopolysaccharide
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?