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3.4.24.B23: stage IV sporulation protein FB

This is an abbreviated version!
For detailed information about stage IV sporulation protein FB, go to the full flat file.

Reaction

implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro-sigma K factor =

Synonyms

More, pro-sigmaK protease, SPOIVFB, SpoIVFB protein

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B23 stage IV sporulation protein FB

Reference

Reference on EC 3.4.24.B23 - stage IV sporulation protein FB

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Jiang, X.; Rubio, A.; Chiba, S.; Pogliano, K.
Engulfment-regulated proteolysis of SpoIIQ: evidence that dual checkpoints control sigma activity
Mol. Microbiol.
58
102-115
2005
Bacillus subtilis, Bacillus subtilis PV79
Manually annotated by BRENDA team
Zhou, R.; Kroos, L.
Serine proteases from two cell types target different components of a complex that governs regulated intramembrane proteolysis of pro-sigmaK during Bacillus subtilis development
Mol. Microbiol.
58
835-846
2005
Bacillus subtilis, Bacillus subtilis PV79
Manually annotated by BRENDA team
Zhou, R.; Cusumano, C.; Sui, D.; Garavito, R.M.; Kroos, L.
Intramembrane proteolytic cleavage of a membrane-tethered transcription factor by a metalloprotease depends on ATP
Proc. Natl. Acad. Sci. USA
106
16174-16179
2009
Bacillus subtilis
Manually annotated by BRENDA team
Chen, G.; Zhang, X.
New insights into S2P signaling cascades: regulation, variation and conservation
Protein Sci.
19
2015-2030
2010
Bacillus subtilis
Manually annotated by BRENDA team
Kroos, L.; Akiyama, Y.
Biochemical and structural insights into intramembrane metalloprotease mechanisms
Biochim. Biophys. Acta
1828
2873-2885
2013
Bacillus subtilis
Manually annotated by BRENDA team
Zhou, R.; Chen, K.; Xiang, X.; Gu, L.; Kroos, L.
Features of pro-sigmaK important for cleavage by SpoIVFB, an intramembrane metalloprotease
J. Bacteriol.
195
2793-2806
2013
Bacillus subtilis
Manually annotated by BRENDA team
Zhang, Y.; Luethy, P.M.; Zhou, R.; Kroos, L.
Residues in conserved loops of intramembrane metalloprotease SpoIVFB interact with residues near the cleavage site in pro-sigmaK
J. Bacteriol.
195
4936-4946
2013
Bacillus subtilis
Manually annotated by BRENDA team
Zhang, Y.; Halder, S.; Kerr, R.A.; Parrell, D.; Ruotolo, B.; Kroos, L.
Complex formed between intramembrane metalloprotease SpoIVFB and its substrate, Pro-sigmaK
J. Biol. Chem.
291
10347-10362
2016
Bacillus subtilis (P26937), Bacillus subtilis 168 (P26937)
Manually annotated by BRENDA team
Halder, S.; Parrell, D.; Whitten, D.; Feig, M.; Kroos, L.
Interaction of intramembrane metalloprotease SpoIVFB with substrate Pro-sigmaK
Proc. Natl. Acad. Sci. USA
114
e10677
2017
Bacillus subtilis (P26937), Bacillus subtilis 168 (P26937)
Manually annotated by BRENDA team