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3.4.24.B2: oligoendopeptidase F

This is an abbreviated version!
For detailed information about oligoendopeptidase F, go to the full flat file.

Word Map on EC 3.4.24.B2

Reaction

proteolytic cleavage of proteins at Leu-Gly =

Synonyms

alkaline endopeptidase, GT-SM3B, LEPI, M03.007, oligopeptidase F, PepF, PepF1, PepF2, PepFBa

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B2 oligoendopeptidase F

Inhibitors

Inhibitors on EC 3.4.24.B2 - oligoendopeptidase F

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
2-mercaptoethanol
14% inhibition at 1 mM
Brij 35
complete inhibition at 1 mM
Brij 58
complete inhibition at 1 mM
Cd2+
inhibits at 10 mM
Co2+
6% inhibition at 1 mM
dithiothreitol
-
-
DTT
42% inhibition at 1 mM
ethylene glycol
34% inhibition at 1%
Fe2+
inhibits at 10 mM
Fe3+
77% inhibition at 1 mM
glycerol
26% inhibition at 5%, 15% ativation at 1%
Guanidine-HCl
22% inhibition at 1 mM
Mn2+
51% inhibition at 1 mM
NaCl
-
0.001 mM decreases enzyme activity by 25%
Ni2+
41% inhibition at 1 mM
Pb2+
inhibits at 10 mM
SDS
48% inhibition at 1 mM, complete inhibition at 10 mM
Triton X-100
37% inhibition at 1%
Triton X-305
98% inhibition at 1%
-
Tween 20
33% inhibition at 0.1%
Tween 40
42% inhibition at 0.1%
Tween 60
38% inhibition at 0.1%
Tween 80
58% inhibition at 0.1%
Zn2+
14% inhibition at 1 mM
additional information
not inhibited by E-64, iodoacetamide, phosphoramidon and pehylmethylsulfonyl fluoride
-