3.4.24.B19: i-AAA protease

This is an abbreviated version!
For detailed information about i-AAA protease, go to the full flat file.

Reaction

proteolytic degradation of proteins =

Synonyms

AAA protease, casein lytic proteinase XP, ClpXP, FtsH4, i-AAA Protease, IAP, IAP-1, M41.004, OSD1 protein, TAT-binding homolog 11, YME1, YME1 AAA protease, Yme1L, Yme1p

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.B19 i-AAA protease

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Results	in table
2	Activating Compound
3	AA Sequence
2	Application
1	CAS Registry Number
7	Cloned(Commentary)
10	Cofactor
14	General Information
1	General Stability
6	Inhibitors
35	Localization
4	Metals/Ions
1	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
143	Organism
17	Protein Variants
3	Purification (Commentary)
6	Reaction
6	Reaction Type
32	Reference
1	Source Tissue
56	Substrates and Products (Substrate)
8	Subunits
42	Synonyms
2	Temperature Optimum [°C]

Cloned

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Cloned on EC 3.4.24.B19 - i-AAA protease

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

-

Arabidopsis thaliana

O80983

754234

expressed in Mus musculus

Saccharomyces cerevisiae

-

734352

expressed in SHSY5Y cells

Saccharomyces cerevisiae

-

733731

expression of N-terminal residues 250-313 of the AAA domain as GST-fusion protein in Escherichia coli

Saccharomyces cerevisiae

-

653335

expression of wild-type and mutant E41Q in deficient mutant cell DELTAyme1, complementation only by the wild-type

Saccharomyces cerevisiae

-

650958

expression of wild-type enzyme in Escherichia coli strain DH5alpha, expression of deletion mutant in Escherichia coli strain BMH 71-18 mut S

Saccharomyces cerevisiae

-

653183

expressed in deltayme1 yeast strain

additional information

-

670047