3.4.24.B17: FtsH endopeptidase

This is an abbreviated version!
For detailed information about FtsH endopeptidase, go to the full flat file.

Reaction

proteolytic degradation of proteins =

Synonyms

cell division protein ftsH, FtsH, FtsH protease, FTSH_ECOLI, HflB, HlB, M41.001, MtFtsH, T.ftsH

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.B17 FtsH endopeptidase

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Results	in table
7	Activating Compound
5	AA Sequence
1	CAS Registry Number
19	Cloned(Commentary)
57	Cofactor
5	Crystallization (Commentary)
2	Expression
18	General Information
18	Inhibitors
6	KM Value [mM]
49	Localization
26	Metals/Ions
3	Molecular Weight [Da]
63	Natural Substrates/ Products (Substrates)
308	Organism
7	pH Optimum
3	Posttranslational Modification
39	Protein Variants
13	Purification (Commentary)
13	Reaction
24	Reaction Type
77	Reference
2	Renatured (Commentary)
12	Specific Activity [micromol/min/mg]
263	Substrates and Products (Substrate)
22	Subunits
100	Synonyms
12	Temperature Optimum [°C]
2	Temperature Range [°C]
8	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.4.24.B17 - FtsH endopeptidase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.0036

Escherichia coli

-

purified recombinant refolded enzyme, substrate protein sigma32

650184

0.014

Escherichia coli

-

purified recombinant fusion protein MF5, ATPase activity

651260

0.055

Escherichia coli

-

purified recombinant fusion protein MF4, ATPase activity

651260

0.056

Escherichia coli

-

purified recombinant fusion protein MF3, ATPase activity

651260

0.07

Escherichia coli

-

purified recombinant fusion protein MF2, ATPase activity

651260

0.113

Escherichia coli

-

purified recombinant mutant G230A

652491

0.122

2 entries

0.349

Escherichia coli

-

purified recombinant mutant F228A

652491

0.735

Escherichia coli

-

purified recombinant wild-type enzyme

652491

1.01

Escherichia coli

-

purified recombinant mutant F228E

652491

additional information

Thermus thermophilus

Q5SI82

-

651768

0.122

Escherichia coli

-

purified recombinant fusion protein MF1, ATPase activity

651260

0.122

Escherichia coli

-

purified recombinant mutant F228K

652491