3.4.24.B17: FtsH endopeptidase

This is an abbreviated version!
For detailed information about FtsH endopeptidase, go to the full flat file.

Reaction

proteolytic degradation of proteins =

Synonyms

cell division protein ftsH, FtsH, FtsH protease, FTSH_ECOLI, HflB, HlB, M41.001, MtFtsH, T.ftsH

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.B17 FtsH endopeptidase

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Results	in table
7	Activating Compound
5	AA Sequence
1	CAS Registry Number
19	Cloned(Commentary)
57	Cofactor
5	Crystallization (Commentary)
2	Expression
18	General Information
18	Inhibitors
6	KM Value [mM]
49	Localization
26	Metals/Ions
3	Molecular Weight [Da]
63	Natural Substrates/ Products (Substrates)
308	Organism
7	pH Optimum
3	Posttranslational Modification
39	Protein Variants
13	Purification (Commentary)
13	Reaction
24	Reaction Type
77	Reference
2	Renatured (Commentary)
12	Specific Activity [micromol/min/mg]
263	Substrates and Products (Substrate)
22	Subunits
100	Synonyms
12	Temperature Optimum [°C]
2	Temperature Range [°C]
8	Turnover Number [1/s]

Cloned

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Cloned on EC 3.4.24.B17 - FtsH endopeptidase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

expressed in Escherichia coli Hms174(DE3) cells

Escherichia coli

-

734211

expressed in Escherichia coli strain A8926

Bacillus subtilis

-

721019

expressed in Escherichia coli strain AR5771

Anabaena sp.

-

712896

expression in Escherichia coli

Escherichia coli

P0AAI3

755341

expression of AAA domain residues 126-398 as tagged protein in strain AR5088

Escherichia coli

-

649174

expression of GST-wild-type enzyme fusion protein, expression of coiled-coil structure mutant enzymes, expression of coiled-coil C-terminus, residues 541-585, as His-tagged peptide

Escherichia coli

-

652822

expression of His-Myc-tagged enzyme

Escherichia coli

-

652391

expression of His-Myc-tagged wild-type and mutant enzymes from strain TY024

Escherichia coli

-

650082

expression of maltose-binding fusion proteins in Escherichia coli

Escherichia coli

-

651260

expression of several mutant enzyme forms

Escherichia coli

-

653608

expression of wild-type and mutant from plasmid

Escherichia coli

P0AAI3

651418

expression of wild-type and mutants

Escherichia coli

-

652491

expression of wild-type and mutants as His-Myc-tagged proteins

Escherichia coli

-

651856

expression of wild-type enzyme in Escherichia coli strain AD465 as His-tagged and Myc-tagged protein

Escherichia coli

-

651232

expression of wild-type tagged with His6- and Myc-tag in Escherichia coli

Escherichia coli

-

649856

ftsH gene, expression as His-tagged enzyme in strain BL21(DE3)

Escherichia coli

-

650184

FtsH is expressed in Escherichia coli as a construct (residues 146-610) lacking the two transmembrane helices

Thermotoga maritima

Q9WZ49

670698

T.ftsH gene, DNA determination and analysis, expression as His-tagged protein in Escherichia coli

Thermus thermophilus

Q5SI82

651768

the MtStsH protein can efficiently complement lethality of DELTAftsH3::kan mutations in Escherichia coli

Mycobacterium tuberculosis

-

668671