3.4.24.B17: FtsH endopeptidase
This is an abbreviated version!
For detailed information about FtsH endopeptidase, go to the full flat file.
Word Map on EC 3.4.24.B17
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3.4.24.B17
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cushing
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cortisol-producing
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matriptase
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ttsps
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pro-hgf
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prkar1a
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ctnnb1
- 3.4.24.B17
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cushing
-
cortisol-producing
- matriptase
-
ttsps
-
pro-hgf
-
prkar1a
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ctnnb1
Reaction
proteolytic degradation of proteins =
Synonyms
cell division protein ftsH, FtsH, FtsH protease, FTSH_ECOLI, HflB, HlB, M41.001, MtFtsH, T.ftsH
ECTree
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Activating Compound
Activating Compound on EC 3.4.24.B17 - FtsH endopeptidase
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alpha-casein
temperature-independent, native protein is slightly, the unfolded protein stimulatory to a higher extent, maximal at 50fold excess
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ATP
ATP-dependent metalloendoprotease belonging to the AAA family (ATPases associated with diverse cellular activities)
dimethylsulfoxid
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induces conformational changes, stimulates with SecY s substrate, at concentration up to 20% v/v, slightly inhibitory with casein as a substrate
Pepsin
temperature-independent, native protein is slightly, the unfolded protein stimulatory to a higher extent, maximal at 50fold excess
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succinate
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stimulates, antagonist of carbonyl cyanide-3-chlorophenylhydrazone
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stimulation by the proton motive force through the transmembrane region
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additional information
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unfolded or uncomplexed protein substrates, protein sigma32 and casein, stimulate 1 to 2fold the wild-type enzyme and the mutants F228K, F228E, and F228A, but not G230A
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