3.4.24.B11: ADAMTS1 endopeptidase

This is an abbreviated version!
For detailed information about ADAMTS1 endopeptidase, go to the full flat file.

Reaction

proteolytic degradation of proteins =

Synonyms

A Disintegrin And Metalloprotease with ThromboSpondin Repeats 1, a disintegrin and metalloprotease with thrombospondin-like motifs, a disintegrin and metalloproteinase with thrombospondin 1, a disintegrin and metalloproteinase with thrombospondin motifs, a disintegrin and metalloproteinase with thrombospondin motifs 1, a disintegrin and metalloproteinase with thrombospondin motifs-1, a disintegrin and metalloproteinase with thrombospondin repeats 1, a disintegrin-like and metalloproteinase domain with thrombospondin type I motifs-1, ADAM metallopeptidase, ADAM-metallopeptidase with thrombospondin type 1 motifs-1, ADAM-TS 1, ADAM-TS1, ADAMTS-1, ADAMTS1, ADAMTS1 matrix metalloproteinase, angiogenesis inhibitor, M12.222, METH-1, METH1, XADAMTS1, Xenopus ortholog of ADAMTS1

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.B11 ADAMTS1 endopeptidase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
8	Activating Compound
5	AA Sequence
16	Application
1	CAS Registry Number
19	Cloned(Commentary)
1	Crystallization (Commentary)
3935	Disease/ Diagnostics
9	Expression
10	General Information
26	Inhibitors
14	Localization
16	Metals/Ions
20	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
72	Organism
4	pH Optimum
7	Posttranslational Modification
12	Protein Variants
11	Purification (Commentary)
4	Reaction
14	Reaction Type
71	Reference
87	Source Tissue
1	Specific Activity [micromol/min/mg]
71	Substrates and Products (Substrate)
11	Subunits
104	Synonyms
5	Temperature Optimum [°C]

Expression

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Expression on EC 3.4.24.B11 - ADAMTS1 endopeptidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Expression Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

EXPRESSION

ORGANISM

UNIPROT

LITERATURE

ADAMTS-1 mRNA expression is strongly, indirectly and progressively upregulated over the period of 30 min to 16 h by vascular endothelial growth factor A

Mus musculus

-

720154

elevated ADAMTS1 expression in endometrial adenocarcinoma, PGF2alpha-FP signalling upregulates ADAMTS1 expression via a calmodulin-NFAT-dependent pathway

Homo sapiens

-

711591

in aggressive and highly plastic melanoma and Ewing sarcoma cells

Homo sapiens

-

711676

incubation of myocytes with ethanol increases Adamt1 mRNA without changing the overall level of Adamts1 protein

Mus musculus

P97857

734360

luteinizing hormone/human chorionic gonadotropin (LH/hCG)-induced gene, follicle-size dependent

Homo sapiens

Q8NE26, Q9UHI8

713020

mRNA expression is increased by forskolin and overexpression of the catalytic subunit of protein kinase A,. Furthermore, treatment with a soluble epidermal growth factor induces mRNA expression in granulosa cells. The enzyme expression is increased at 6 to 24 hours after human chorionic gonadotropin in granulosa cells

Bos taurus

A7MB07

733733

overexpression promotes bone metastasis

Homo sapiens

-

712107

transiently expressed in the infarcted heart, when stimulated with tissue necrosis factor, the expression level of mRNA rapidly increases

Homo sapiens

-

710774

upregulated in endothelial cells by shear stress

Homo sapiens

-

712562