3.4.24.83: anthrax lethal factor endopeptidase

This is an abbreviated version, for detailed information about anthrax lethal factor endopeptidase, go to the full flat file.

Reaction

Preferred amino acids around the cleavage site can be denoted BBBBxHx-/-H, in which B denotes Arg or Lys, H denotes a hydrophobic amino acid, and x is any amino acid. The only known protein substrates are mitogen-activated protein (MAP) kinase kinases =

Synonyms

anthrax lethal factor, anthrax lethal factor protease, anthrax lethal toxin, anthrax LF, Bacillus anthracis lethal toxin, lethal factor, lethal factor of anthrax toxin, lethal toxin, LeTx, LF, LTx

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.83 anthrax lethal factor endopeptidase