3.4.24.79: pappalysin-1

This is an abbreviated version!
For detailed information about pappalysin-1, go to the full flat file.

Word Map on EC 3.4.24.79

3.4.24.79

women

trimester

fetal

chorionic

translucency

nuchal

first-trimester

singleton

trisomy

artery

ultrasound

beta-hcg

uterine

preeclampsia

gonadotrophin

prenatal

false-positive

aneuploidy

beta-human

coronary

fetuses

doppler

pulsatility

preterm

igfbps

igf-i

igf-binding

crown-rump

second-trimester

inhibin

alpha-fetoprotein

centile

obstetric

screen-positive

stillbirth

amniocentesis

euploid

sonograph

venosus

metzincin

afro-caribbeans

medicine

pregnancy-specific

sflt-1

adam12

small-for-gestational-age

monochorionic

delfia

triploidy

molecular biology

diagnostics

oestriol

small-for-gestational

Reaction

Cleavage of the Met135-/-Lys bond in insulin-like growth factor binding protein (IGFBP)-4, and the Ser143-/-Lys bond in IGFBP-5 =

Synonyms

IGF binding protein-4 protease, IGF binding protein-4 specific proteinase, IGF-BP-4 proteinase, IGFBP proteinase, IGFBP-4 protease, insulin-like growth factor binding protein-4 protease, insulin-like growth factor-binding protein proteinase, More, PAPP-A, PAPP-A2, PAPPA, pappalysin-1, pregnancy associated plasma protein-A, pregnancy-associated plasma protein A, pregnancy-associated plasma protein-A, pregnancy-associated plasma protein-A2, pregnancy-related serine protease, protein IGF-BP 4 proteinase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.79 pappalysin-1

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Results	in table
11	Activating Compound
26	AA Sequence
17	Application
1	CAS Registry Number
8	Cloned(Commentary)
4506	Disease/ Diagnostics
8	Expression
7	General Information
3	General Stability
25	Inhibitors
2	Ki Value [mM]
7	KM Value [mM]
15	Localization
22	Metals/Ions
5	Molecular Weight [Da]
50	Natural Substrates/ Products (Substrates)
67	Organism
8	PDB ID
5	pH Optimum
2	Posttranslational Modification
10	Protein Variants
4	Purification (Commentary)
6	Reaction
67	Reference
2	Renatured (Commentary)
82	Source Tissue
4	Specific Activity [micromol/min/mg]
2	Storage Stability
82	Substrates and Products (Substrate)
5	Subunits
113	Synonyms
5	Temperature Optimum [°C]
3	Temperature Stability [°C]
5	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.24.79 - pappalysin-1

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IGF binding protein-4 protease

IGF binding protein-4 specific proteinase

IGF-BP-4 proteinase

IGFBP proteinase

Homo sapiens

684023

IGFBP-4 protease

2 entries

insulin-like growth factor binding protein-4 protease

insulin-like growth factor-binding protein proteinase

PAPP-A

PAPP-A2

PAPPA

pappalysin-1

pregnancy associated plasma protein-A

3 entries

pregnancy-associated plasma protein A

2 entries

pregnancy-associated plasma protein-A

12 entries

pregnancy-associated plasma protein-A2

Homo sapiens

700237

pregnancy-related serine protease

protein IGF-BP 4 proteinase

additional information

Homo sapiens

PAPP-A and PAPP-A2 are unique members in the group of laminin G proteins, the pappalysins represent examples where LG modules are associated with proteinases

684023