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3.4.24.79: pappalysin-1

This is an abbreviated version!
For detailed information about pappalysin-1, go to the full flat file.

Word Map on EC 3.4.24.79

Reaction

Cleavage of the Met135-/-Lys bond in insulin-like growth factor binding protein (IGFBP)-4, and the Ser143-/-Lys bond in IGFBP-5 =

Synonyms

IGF binding protein-4 protease, IGF binding protein-4 specific proteinase, IGF-BP-4 proteinase, IGFBP proteinase, IGFBP-4 protease, insulin-like growth factor binding protein-4 protease, insulin-like growth factor-binding protein proteinase, More, PAPP-A, PAPP-A2, PAPPA, pappalysin-1, pregnancy associated plasma protein-A, pregnancy-associated plasma protein A, pregnancy-associated plasma protein-A, pregnancy-associated plasma protein-A2, pregnancy-related serine protease, protein IGF-BP 4 proteinase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.79 pappalysin-1

Source Tissue

Source Tissue on EC 3.4.24.79 - pappalysin-1

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
the enzyme is extracted from plaque tissue samples of endarterectomy and aneurysm patients
Manually annotated by BRENDA team
-
of bone fracture in the mid-shaft
Manually annotated by BRENDA team
-
enzyme expression during follicular development and in cell culture
Manually annotated by BRENDA team
additional information