3.4.24.74: fragilysin

This is an abbreviated version!
For detailed information about fragilysin, go to the full flat file.

Word Map on EC 3.4.24.74

3.4.24.74

staphylococcal

aureus

enterotoxigenic

heat-labile

superantigens

heat-stable

cholera

diarrhea

clostridium

perfringens

lymphocyte

t-cells

vaccine

poisoning

mucosal

milk

vibrio

ifn-gamma

outbreak

serotype

sta

serogroups

anergy

foodborne

enteropathogenic

ganglioside

gm1

hydrophila

exotoxin

methicillin-resistant

hemolysin

cytotoxin

ileal

toxigenic

stool

agglutination

emetic

enterocolitica

shiga

toxin-producing

retail

coagulase

rotavirus

b-subunits

medicine

methicillin

holotoxin

antitoxin

toxoid

pyrogen

anti-cd3

Reaction

Broad proteolytic specificity, bonds hydrolysed including -Gly-/-Leu-, -Met-/-Leu-, -Phe-/-Leu-, -Cys-/-Leu-, Leu-/-Gly =

Synonyms

B. fragilis enterotoxin, Baceroides fragilis enterotoxin, Bacillus fragilis toxin, Bacteroides fragilis enterotoxin, Bacteroides fragilis enterotoxin-2, Bacteroides fragilis toxin, BFT, BFT-1, BFT-2, BFT-3, BFT2, Enterotoxin, FRA3, fragilysin-2, fragilysin-3, Korea-BFT, More, toxin-2

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.74 fragilysin

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Results	in table
2	Activating Compound
25	AA Sequence
8	Application
1	CAS Registry Number
15	Cloned(Commentary)
1	Crystallization (Commentary)
8	General Information
3	General Stability
36	Inhibitors
10	Localization
8	Metals/Ions
16	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
43	Organism
4	PDB ID
2	pH Optimum
3	pH Stability
1	pI Value
18	Protein Variants
15	Purification (Commentary)
1	Reaction
1	Reaction Type
41	Reference
4	Source Tissue
5	Specific Activity [micromol/min/mg]
1	Storage Stability
74	Substrates and Products (Substrate)
14	Subunits
67	Synonyms
1	Temperature Optimum [°C]
5	Temperature Stability [°C]

Molecular Weight

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Molecular Weight on EC 3.4.24.74 - fragilysin

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18000 - 22000

gel fitration

19000

1 * 19000, SDS-PAGE

20000

20600

21000

25000

x * 25000, mature enzyme, SDS-PAGE

44000

44400

preproprotein

additional information

Bacteroides fragilis

analysis of BFT-2 by native PAGE reveals bands at 36000 Da, 90000 Da and 200000 Da. Both the 36000 Da and higher-molecular-mass bands are biologically active when tested in the HT29/C1 cell assay

651483