3.4.24.7: interstitial collagenase
This is an abbreviated version!
For detailed information about interstitial collagenase, go to the full flat file.
Word Map on EC 3.4.24.7
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3.4.24.7
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metalloproteinases
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mmp-2
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metastasis
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gelatinase
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timp-1
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zymography
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endothelial
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gelatin
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angiogenesis
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cartilage
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fibrosis
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basement
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type-1
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stromelysins
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invasiveness
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arthritis
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dermal
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plasminogen
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gelatinolytic
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prommp-2
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proteinases
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integrins
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matrigel
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synovial
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pericellular
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fibrosarcoma
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mt-mmp
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fibrillar
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procollagen
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chondrocytes
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matrix-degrading
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collagenase-3
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progelatinase
-
proenzyme
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invadopodia
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laminin-5
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analysis
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membrane-tethered
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pharmacology
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drug development
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triple-helical
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diagnostics
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photoaging
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medicine
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batimastat
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procollagenase
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podosomes
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furin
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hemopexin
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collagen-rich
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reck
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cortactin
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pro-matrix
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synthesis
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matrilysin
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emmprin
- 3.4.24.7
- metalloproteinases
- mmp-2
- metastasis
- gelatinase
- timp-1
-
zymography
- endothelial
- gelatin
- angiogenesis
- cartilage
- fibrosis
-
basement
- type-1
- stromelysins
-
invasiveness
- arthritis
- dermal
- plasminogen
-
gelatinolytic
- prommp-2
- proteinases
- integrins
- matrigel
- synovial
-
pericellular
- fibrosarcoma
-
mt-mmp
-
fibrillar
- procollagen
- chondrocytes
-
matrix-degrading
- collagenase-3
- progelatinase
- proenzyme
-
invadopodia
- laminin-5
- analysis
-
membrane-tethered
- pharmacology
- drug development
-
triple-helical
- diagnostics
-
photoaging
- medicine
- batimastat
- procollagenase
-
podosomes
- furin
- hemopexin
-
collagen-rich
- reck
- cortactin
-
pro-matrix
- synthesis
- matrilysin
-
emmprin
Reaction
Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-/-Ile in the alpha1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue =
Synonyms
azocollase, collagen peptidase, collagen protease, collagenase, collagenase 1, collagenase A, collagenase MMP-1, collagenase-1, collagenolytic matrix metalloproteinase, EC 3.4.99.5, ect-MMP-14, Fibroblast collagenase, HSFC, kollaza, macrophage matrix metalloproteinase, matrix metalloproteinase 1, matrix metalloproteinase-1, matrix metalloproteinase-18, matrix-metalloproteinase-1, membrane-type 1-MMP, metallocollagenase, metalloproteinase-1, MMP-1, MMP-12, MMP-14, MMP-1A, mmp1, MT1-MMP, Myocardial collagenase, nucleolysin, soycollagestin, TC1, tumor collagenase, vertebrate collagenase