Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
MMP-1 is upregulated by TGF-beta, EGF and IL-1beta
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
cell line JJ, increased MMP1 expression in chondrosarcoma, mechanism, overview
brenda
-
mucosa, immunohistochemic analysis of MMP-1 and TIMP-1 levels, overview. Overall plasma levels of MMP-1 and TIMP-1 in ulcerative colitis patients are significantly higher than those of the control group
brenda
-
acceleration of matrix metalloproteinase-1 production by oxidized low-sensity lipoprotein and 4-hydroxynonenal
brenda
-
-
brenda
-
primary
brenda
-
MMP-1 is expressed by migrating enterocytes bordering intestinal ulcers. In the fetal gut model, MMP-1 expression by migrating enterocytes is detected
brenda
-
-
brenda
-
-
brenda
-
primary epithelial ovarian tumor cell
brenda
-
MMP-14 is expressed and active in cultured ES2 cells. ES2 cells also exhibit MMP-dependent invasion of and proliferation within three-dimensional collagen gels
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
immortalized human keratinocyte cells
brenda
-
MMP-10 and MMP-1 are up-regulated in HaCaT II-4 cells
brenda
-
the MMP-1 levels are altered in the left ventricle and serum in case of hypertrophy through hyperthyroid conditions with 3,5,3'-triiodo-L-thyroine or dexamethasone application, tissue distribution, overview
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
glycine-extended gastrin renders colon cancer cells more invasive by increasing MMP-I expression via the putative glycine-extended gastrin receptor
brenda
-
primary, monocyte-derived
brenda
-
high MMP-1 level
brenda
-
-
brenda
-
Muller glia cell line
brenda
-
saphenous vein smooth muscle
brenda
-
-
brenda
-
-
brenda
-
UM1 and UM2 are oral tongue squamous cell carcinoma cell lines
brenda
-
ovarian clear cell carcinoma cell
brenda
-
-
brenda
-
-
brenda
-
follicular expression of MMP-1 increases following the gonadotropin surge. Abundance of MMP-1 mRNA increases at 6, 12, and 48 h post-gonadotropin releasing hormone injection. MMP-1 is localized to granulosal and thecal layers of preovulatory follicles. MMP-1 is increased in bovine preovulatory follicles following the gonadotropin surge
brenda
-
enzyme expression is significantly stronger in the epithelium than in the stroma
brenda
-
brenda
-
the mean salivary MMP-1 concentration in patients with chronic periodontitis is significantly higher before and after treatment with aprotinin, as compared to healthy subjects
brenda
-
-
brenda
-
disruption of caveolae by addition of methyl-beta-cyclodextrin results in a dramatic decline in both motility and invasion abilities of cells with concomitant increase in secreted MMP-2 expression and expression levels of MMP-1 and MMP-9
brenda
-
disruption of caveolae by addition of methyl-beta-cyclodextrin results in a dramatic decline in both motility and invasion abilities of cells with concomitant increase in secreted MMP-2 expression and expression levels of MMP-1 and MMP-9
brenda
-
SCL-1 cell. MMP-1 is upregulated 4 h after UVA and 16 h after UVB irradiation of tumor cells. Incubation of cells with the MEK1/2 inhibitor U0126 or the p38 inhibitor SB202190 abolishes the UVA and UVB mediated induction of MMP-1
brenda
-
a human chondrosarcoma cell line
brenda
-
rheumatoid
brenda
-
-
brenda
-
fibroblast-like, from rheumatoid arthritis patients
brenda
-
-
brenda
-
from Achilles tendon, immunohistochemic analysis of MMP-1, overview
brenda
-
leg ulcer tissue from patients with chronic venous insufficiency
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
-
brenda
-
in the center of granulomas
brenda
-
MMP-1 is upregulated in the infarcted tissue compared to healthy control areas
brenda
-
-
brenda
recombinant enzyme
brenda
-
purified MMP-1 from synovial fibroblasts
brenda
-
recombinant MMP-1
brenda
-
of interleukin-1-treated dermal fibroblasts
brenda
-
of rheumatoid synovial cells stimulated with rabbit macrophage-conditioned medium
brenda
-
-
95818, 95824, 95829, 95833, 95834, 655414, 656898, 683988, 699874, 708511, 708788, 709025, 709482, 717074 brenda
-
brenda
-
-
brenda
-
brenda
-
fibroblasts
brenda
-
dermal
brenda
dermal fibroblast
brenda
-
gingival
brenda
-
overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release
brenda
-
primary cultured corneal and tenon's fibroblast
brenda
-
production of MMP-1 by keloid fibroblasts is 6fold greater than that of normal dermal fibroblasts. The production of MMP-1 is decreased by addition of TGF-beta1 to cultured keloid fibroblasts, while it is increased when anti-TGF-beta1 antibody is added to the culture
brenda
-
dermal, quantitative MMP-1 expression analysis by RT-PCR
brenda
-
from lung
brenda
-
healthy dermal fibroblasts and cultured Xeroderma pigmentosum-C fibroblasts, increased MMP1 expression in cultured XP-C fibroblasts results from MMP1 mRNA accumulation and enhanced transcriptional activity of the MMP1 gene promoter, overview
brenda
-
NHDFs and NB1RGBs
brenda
-
primary lung fibroblast cell lines
brenda
-
dermal, primary
brenda
-
gingival, gingival fibroblasts produce MMP-1 in response to inflammatory cytokines, such as TNF and interleukin-1
brenda
-
synovial fibroblast
brenda
-
expression of MMP-1 is markedly increased by both onion extract and quercetin in vitro in human skin fibroblasts
brenda
primary human neonatal dermal fibroblasts
brenda
-
-
brenda
-
expression of MMP-1 is markedly increased by both onion extract and quercetin in vivo in hairless mice
brenda
-
-
brenda
-
brenda
-
fibroblasts
brenda
-
-
brenda
-
connective tissue
brenda
-
-
brenda
-
after hyperglycaemic treatment, expression of matrix metalloproteinase-1 and alpha2beta1 integrin is significantly downregulated
brenda
-
epidermal, primary, from foreskin
brenda
-
-
brenda
-
alveolar mucosa expression from HIV1+ smokers with early emphysema is significantly higher than in HIV1- smokers with early emphysema. Among the HIV- groups, compared with HIV1- healthy nonsmokers, smoking do not increase aqlveolar mucosa MMP-1 gene expression in HIV1- healthy smokers and HIV1- smokers with early emphysema, independent of whether emphysema is present or not. HIV1+ individuals with early emphysema have significantly increased expression of MMP-1 compared with all 3 groups of HIV1- individuals, including those with early emphysema
brenda
-
-
brenda
-
treatment of with 30 mM of 15-deoxy-DELTA12,14-prostaglandin J2 increases the expression of heme oxygenase-1, which precedes the induction of matrix metalloproteinases. The 15-deoxy-DELTA12,14-prostaglandin J2-induced upregulation of MMP-1 is abrogated by the heme oxygenase-1 inhibitor zinc protoporphyrin IX as well as introduction of heme oxygenase-1 short interfering RNA. Heme oxygenase-1 inducers, such as cobalt protoporphyrin IX and hemin, upregulate the expression of MMP-1. Overexpression of heme oxygenase-1 in the MCF-7 cells causes the induction of MMP-1 expression. Treatment with the heme oxygenase-1 inhibitor zinc protoporphyrin IX abolishes the migrative phenotype of 15-deoxy-DELTA12,14-prostaglandin J2-treated MCF-7 cells
brenda
-
-
brenda
-
treatment of with 30 mM of 15-deoxy-DELTA12,14-prostaglandin J2 increases the expression of heme oxygenase-1, which precedes the induction of matrix metalloproteinases. The 15-deoxy-DELTA12,14-prostaglandin J2-induced upregulation of MMP-1 is abrogated by the heme oxygenase-1 inhibitor zinc protoporphyrin IX as well as introduction of heme oxygenase-1 short interfering RNA. Heme oxygenase-1 inducers, such as cobalt protoporphyrin IX and hemin, upregulate the expression of MMP-1
brenda
-
VMM5 cells, VMM12cells and VMM39. Constitutive overexpression of collagenase 1 is mediated by the ERK pathway in invasive melanoma cells
brenda
-
of invasive melanomas
brenda
of bone marrow
brenda
-
of bone marrow
-
brenda
-
-
brenda
-
primary
brenda
-
-
brenda
-
expression profile of MMPs/TIMP-1 after myocardial infarction, angiotensin II receptor blockade improves MMPs/TIMP-1 balance, overview
brenda
-
collagen-induced arthritis hind paw sections as a model of human rheumatoid arthritis
brenda
-
collagen-induced arthritis hind paw sections as a model of human rheumatoid arthritis
-
brenda
-
immunohistochemic analysis of MMP-1 and TIMP-1 levels, overview. Overall plasma levels of MMP-1 and TIMP-1 in ulcerative colitis patients are significantly higher than those of the control group
brenda
-
no differences in MMP-1 in the plasma of hypertensive versus normotensive subjects
brenda
-
-
brenda
-
MMP-1 is progressively decreased from prostate intraepithelial neoplasia to prostate carcinoma
brenda
-
-
brenda
-
-
95823, 95824, 95825, 95829, 95832, 683221, 683451, 683988, 708425, 708788, 709482, 709591, 717678 brenda
-
brenda
-
from the lateral thoracic area of a 230 day fetal calf
brenda
-
cell culture
brenda
-
all-trans retinoic acid suppresses matrix metalloproteinase activity in diabetic skin
brenda
-
from mammary plastic surgery, MMP1 expression is increased in Xeroderma pigmentosum, a rare, recessively inherited genetic disease characterized by skin cancer proneness and premature aging in photoexposed area, overview
brenda
-
cell culture
brenda
-
-
brenda
-
-
brenda
-
brenda
-
cell culture
brenda
-
-
-
brenda
Frog
-
-
brenda
Frog
-
backskin
brenda
-
tail
brenda
-
presence of high glucose levels and interferon gamma in culture medium have a synergistic effect on the expression of matrix metalloproteinases MMP-1, MMP-9 and interleukin-1beta. High glucose also enhances interferon gamma-induced priming effect on lipopolysaccharide-stimulated MMP-1 secretion. High glucose and interferon gamma exert the synergistic effect on MMP-1 expression by enhancing STAT1 phosphorylation and STAT1 transcriptional activity
brenda
-
mononuclear phagocytes
brenda
-
-
brenda
-
MMP-1 is upregulated by EGF
brenda
additional information
-
MMP-1 expression analysis in gingival tissue, overview
brenda
additional information
-
MMP-1 is downregulated 4fold during trophoblast differentiation, reduced MMP-1 expression in pre-eclampsia and fetal growth restriction
brenda
additional information
-
overexpression of both ADAMTS1 and MMP-1 together increases osteolytic bone metastases, while overexpression of ADAMTS or MMP-1 alone has no effect
brenda
additional information
-
selective cell-dependent MMP secretion
brenda
additional information
-
MMP-1A is strongly expressed in tumor and arthritis specimens, expression patterns of MMP-1A in a variety of healthy, cancerous and arthritic murine tissues, overview
brenda
additional information
-
MMP-1A is strongly expressed in tumor and arthritis specimens, expression patterns of MMP-1A in a variety of healthy, cancerous and arthritic murine tissues, overview
-
brenda
additional information
detection of collagen deposition and MMP-1 secretion in rat-1 fibroblasts
brenda