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3.4.24.68: tentoxilysin

This is an abbreviated version!
For detailed information about tentoxilysin, go to the full flat file.

Word Map on EC 3.4.24.68

Reaction

Hydrolysis of -Gln76-/-Phe- bond in synaptobrevin (also known as neuronal vesicle-associated membrane protein, VAMP) =

Synonyms

TeNT, TeNT-Hc, TeNT-LC protein, Tentoxylysin, tetanospasmin, Tetanus neurotoxin, tetanus toxin, TetX

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.68 tentoxilysin

Cloned

Cloned on EC 3.4.24.68 - tentoxilysin

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
Clostridium tetani
-
expressed in Escherichia coli
-
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli JM101 using three different plasmid vectors
-
mutant enzyme R372A/Y375F fused to beta-lactamase, expressed in Escherichia coli BL21(DE3) cells
-
tetanus neurotoxin light chain, expressed in Escherichia coli
-
the C-terminal domain bound to Bcl-2 protein is expressed in COS-7 cells and Escherichia coli BL21(DE3)pLysS cells
-
the heavy chain fragment is expressed in Escherichia coli BL21(DE3) cells
-