3.4.24.65: macrophage elastase
This is an abbreviated version!
For detailed information about macrophage elastase, go to the full flat file.
Word Map on EC 3.4.24.65
-
3.4.24.65
-
metalloproteinases
-
mmp-9
-
pulmonary
-
emphysema
-
collagen
-
alveolar
-
elastin
-
fibrosis
-
smoke
-
airway
-
timp-1
-
cigarette
-
lavage
-
bronchoalveolar
-
endothelial
-
metastasis
-
aortic
-
tnf
-
artery
-
chemokine
-
monocyte
-
smoking
-
plaque
-
aneurysm
-
angiogenesis
-
atherosclerotic
-
zymography
-
smoke-induced
-
elastolytic
-
proteinases
-
plasminogen
-
asthma
-
rupture
-
angiostatin
-
bal
-
instil
-
urokinase-type
-
matrilysin
-
airspace
-
mt1-mmp
-
cs-induced
-
elastases
-
smoke-exposed
-
emphysematous
-
diagnostics
-
drug development
-
elastase-induced
-
collagenase-3
-
cs-exposed
-
airflow
-
medicine
-
pharmacology
-
matrix-degrading
-
analysis
- 3.4.24.65
- metalloproteinases
- mmp-9
- pulmonary
- emphysema
- collagen
-
alveolar
- elastin
- fibrosis
-
smoke
- airway
- timp-1
-
cigarette
-
lavage
-
bronchoalveolar
- endothelial
- metastasis
- aortic
- tnf
- artery
- chemokine
- monocyte
-
smoking
- plaque
- aneurysm
- angiogenesis
- atherosclerotic
-
zymography
-
smoke-induced
-
elastolytic
- proteinases
- plasminogen
- asthma
-
rupture
- angiostatin
- bal
-
instil
-
urokinase-type
- matrilysin
-
airspace
- mt1-mmp
-
cs-induced
- elastases
-
smoke-exposed
-
emphysematous
- diagnostics
- drug development
-
elastase-induced
- collagenase-3
-
cs-exposed
-
airflow
- medicine
- pharmacology
-
matrix-degrading
- analysis
Reaction
Hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at -Ala14-/-Leu- and -Tyr16-/-Leu- in the B chain of insulin =
Synonyms
HME, hMMP-12, human macrophage elastase, Human macrophage metalloelastase, human metalloelastase, Macrophage elastase, macrophage matrix metalloproteinase, macrophage metalloelastase, macrophage-specific metalloelastase, matrix metalloproteinase 12, Matrix metalloproteinase-12, ME, Metalloelastase, MME, MMP-12, MMP12, More, mouse macrophage metalloelastase, rHME
ECTree
3.4.24.65 macrophage elastaseAdvanced search results
results (
results (Localization
Localization on EC 3.4.24.65 - macrophage elastase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
LOCALIZATION 
ORGANISM
UNIPROT
COMMENTARY 
GeneOntology No.
LITERATURE
SOURCE
-
glomerular basement membrane. Irregular glomerular basement membrane that characterizes Alport syndrome may be mediated, in part, by focal degradation of glomerular basement membrane due to MMP dysregulation, in particular, MMP-12
additional information
-
MMP12, in contrast to other MMPs, can act intracellularly rather than extracellularly. The majority of MMP12 is secreted, MMP12 might then bind to the bacteria outside the cell prior to phagocytosis
-
