3.4.24.64: mitochondrial processing peptidase

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For detailed information about mitochondrial processing peptidase, go to the full flat file.

Word Map on EC 3.4.24.64

3.4.24.64

presequence

nuclear-encoded

preproteins

intermembrane

frataxin

metalloendopeptidase

friedreich

matrix-targeting

hxxeh

mas1

plumbaginifolia

nuclearly

matrix-localized

intermediate-sized

agriculture

Reaction

Release of N-terminal targetting peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2 =

Synonyms

Alpha-MPP, Atp23, Beta-MPP, EC 3.4.99.41, General mitochondrial processing peptidase, GPP, HA1523, HPP, Imp1, Imp2, inner membrane peptidase processing enzyme, Mas1, Mas2, Matrix peptidase, Matrix processing peptidase, Matrix processing proteinase, Mitochondrial chelator-sensitive protease, mitochondrial processing peptidase, mitochondrial processing peptidase-alpha protein, mitochondrial processing protease, Mitochondrial protein precursor-processing proteinase, MMP-beta, More, MPP, MPP-alpha, P-52, P-55, PEP, Plsp1, Plsp2, PMPCA, Processing enhancing peptidase, processing enhancing protein, processing peptidase, Proteinase, mitochondrial protein precursor-processing, thylakoidal processing peptidase, TPP, TTHA1264

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.64 mitochondrial processing peptidase

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Results	in table
2	Activating Compound
1985	AA Sequence
2	Application
1	CAS Registry Number
35	Cloned(Commentary)
4	Crystallization (Commentary)
10	Disease/ Diagnostics
15	General Information
6	General Stability
68	Inhibitors
43	KM Value [mM]
99	Localization
49	Metals/Ions
36	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
105	Organism
32	PDB ID
9	pH Optimum
2	pH Range
3	Posttranslational Modification
63	Protein Variants
39	Purification (Commentary)
10	Reaction
1	Reaction Type
96	Reference
20	Source Tissue
15	Specific Activity [micromol/min/mg]
4	Storage Stability
241	Substrates and Products (Substrate)
43	Subunits
82	Synonyms
9	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
30	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.4.24.64 - mitochondrial processing peptidase

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0.000001

Saccharomyces cerevisiae

artificial fusion protein

31396

0.000003

Saccharomyces cerevisiae

P25-peptide

31396

0.0000298

Neurospora crassa

ATP synthase subunits 2 and 9

31388

0.0023

Trichomonas vaginalis

approx., non-specified fluorescent peptide substrate based on the Trichomonas vaginalis adenylate kinase presequence, processing activity measured for the alpha subunit of HPP when associated with beta subunit of HPP

700914

1.785

Saccharomyces cerevisiae

strain JKR 102(YEp13-MAS1), overexpressing MAS1

31396

2.35

Saccharomyces cerevisiae

strain JKR 102

31396

23.44

Saccharomyces cerevisiae

strain JKR 102(YEp13-MAS1 plus pCF35-MAS2), overexpressing MAS1 and MAS2

31396

26.78

Saccharomyces cerevisiae

strain VGA

31396

4.688

Saccharomyces cerevisiae

strain JKR 102(pCF35-MAS2), overexpressing MAS2

31396

additional information

6 entries