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3.4.24.62: magnolysin

This is an abbreviated version!
For detailed information about magnolysin, go to the full flat file.

Reaction

Hydrolysis of polypeptides with Arg or Lys in P1 and P2, e.g. to hydrolyse pro-oxytocin at -Lys-Arg-/-Ala-Val-. The specificity further depends on the organization of a beta-turn-alpha-helix of nine or additional information residues containing the paired basic amino acids near the centre =

Synonyms

Bovine neurosecretory granule protease cleaving pro-oxytocin/neurophysin, pro-ocytocin convertase, pro-ocytocin/neurophysin-converting enzyme, Pro-oxytocin convertase, Pro-oxytocin/neurophysin convertase, Proteinase, prooxyphysin

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.62 magnolysin

Molecular Weight

Molecular Weight on EC 3.4.24.62 - magnolysin

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
52000
-
bovine, PAGE, 2 isoforms, MW 52000 and 58000
52000 - 58000
-
bovine, gel filtration
55000 - 65000
58000
-
bovine, PAGE, 2 isoforms, MW 52000 and 58000
60000
-
human