3.4.24.60: dactylysin

This is an abbreviated version, for detailed information about dactylysin, go to the full flat file.

Reaction

Hydrolysis of peptides of at least six residues, with bulky hydrophobic residues in the P1' position. Shows a preference for hydrophobic doublets such as -Phe-/-Phe- and -Phe-/-Leu- in somatostatin-(1-14)-peptide and dynorphin A-(1-6)-peptide, respectively =

Synonyms

Peptide hormone inactivating endopeptidase, peptide hormone inactivating enzyme, PHIE

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.60 dactylysin