3.4.24.59: mitochondrial intermediate peptidase

This is an abbreviated version, for detailed information about mitochondrial intermediate peptidase, go to the full flat file.

Reaction

release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion =

Synonyms

hMIP, Icp55, MIP, MIP1, MIPEP, mitochondrial intermediate peptidase, OCT1, octapeptidyl aminopeptidase 1, Proteinase, mitochondrial intermediate precursor-processing

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.59 mitochondrial intermediate peptidase

Purification

Purification on EC 3.4.24.59 - mitochondrial intermediate peptidase

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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
affinity chromatography using Ni-Sepharose resin and ion exchange chromatography with a Hi-trap resource Q column
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affinity purified
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Ni-Sepharose column chromatography and Resource Q column chromatography
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purified 2250fold to homogeneity
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recombinant MIPEP protein is purified from baculovirus-infected Sf9 cells
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