3.4.24.59: mitochondrial intermediate peptidase

This is an abbreviated version, for detailed information about mitochondrial intermediate peptidase, go to the full flat file.

Reaction

release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion =

Synonyms

hMIP, Icp55, MIP, MIP1, MIPEP, mitochondrial intermediate peptidase, OCT1, octapeptidyl aminopeptidase 1, Proteinase, mitochondrial intermediate precursor-processing

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.59 mitochondrial intermediate peptidase

Natural Substrates Products

Natural Substrates Products on EC 3.4.24.59 - mitochondrial intermediate peptidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
cytochrome c oxidase 4 precursor protein + H2O
mature cytochrome c oxidase + propeptide
show the reaction diagram
-
enzyme inhibition leads to prevention of the normal processing of the precursor of cytochrome c oxidase, i.e. COX, subunit 4 and induced COX degradation, overview
-
-
?
frataxin + H2O
?
show the reaction diagram
-
-
-
-
?
Mitochondrial intermediate proteins + H2O
?
show the reaction diagram
Precursor proteins that have already been processed by mitochondrial processing peptidase + H2O
?
show the reaction diagram