3.4.24.59: mitochondrial intermediate peptidase

This is an abbreviated version, for detailed information about mitochondrial intermediate peptidase, go to the full flat file.

Reaction

release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion =

Synonyms

hMIP, Icp55, MIP, MIP1, MIPEP, mitochondrial intermediate peptidase, OCT1, octapeptidyl aminopeptidase 1, Proteinase, mitochondrial intermediate precursor-processing

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.59 mitochondrial intermediate peptidase

KCat KM Value

KCat KM Value on EC 3.4.24.59 - mitochondrial intermediate peptidase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
17
Abz-FQTKVAAK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
130
Abz-FRSGQPLQNKVQLQ-ED(Dnp)
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
28
Abz-FSSKTTVK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
40
Abz-GFSPFRQ-EDDnp
-
pH 7.4, 37°C, 0.1 mM DTT
50
Abz-IKQSSLLK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
45
Abz-MTAALKTK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
22
Abz-NLMKKSTK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
11
Abz-QPLANKVQ-ED(Dnp)
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
29
Abz-QPLQAKVQ-ED(Dnp)
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
21
Abz-QPLQNKVQ-ED(Dnp)
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
82
Abz-TTKLKAAK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
5
Abz-VAAQTKTK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
44
Abz-VISSRLEK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
124
Abz-VRNFRSGQPLQNKVQED(Dnp)
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C
0.53
Abz-WTTGGKAK(Dnp)-NH2
-
in 50 mM Tris, 100 mM NaCl, pH 8.0, at 25°C