3.4.24.58: russellysin

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For detailed information about russellysin, go to the full flat file.

Reaction

Specifically activates several components of the blood clotting system, including coagulation factor X, coagulation factor IX and protein C by cleavage of -Arg-/- bonds. Has no action on insulin B chain =

Synonyms

Blood-coagulation factor X activating enzyme, EC 3.4.21.23, Metalloproteinase RVV-x, Proteinase, Vipera russelli, Russell's viper blood coagulation factor X activator, Russell's Viper venom factor X activator, Russell's viper venom factor X activator, RVV-X, Russell`s viper venom coagulation factor X-activating enzyme, Russell�s viper venom factor X activator, RVV-X, snake venom protease

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.58 russellysin

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Results	in table
4	AA Sequence
2	Application
1	CAS Registry Number
1	Crystallization (Commentary)
6	Inhibitors
1	KM Value [mM]
2	Localization
7	Metals/Ions
8	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
8	Organism
1	PDB ID
2	pH Optimum
1	pH Range
3	Posttranslational Modification
3	Purification (Commentary)
1	Reaction
1	Reaction Type
8	Reference
7	Source Tissue
1	Specific Activity [micromol/min/mg]
16	Substrates and Products (Substrate)
3	Subunits
16	Synonyms
1	Temperature Optimum [°C]

Molecular Weight

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Molecular Weight on EC 3.4.24.58 - russellysin

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MOLECULAR WEIGHT

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

124000

Daboia russelii

-

Vipera russelli, sedimentation equilibrium centrifugation

31349

18000

Protobothrops mucrosquamatus

-

light chain

668852

21000

Protobothrops mucrosquamatus

-

light chain

668852

59000

2 entries

60000

Daboia russelii

-

2 * 60000, Vipera russelli, SDS-PAGE in absence and presence of 2-mercaptoethanol

31349

79000

Daboia russelii

-

Vipera russelli

31350

93000

Daboia siamensis

Q7LZ61; Q4PRD1; Q4PRD2

-

754969

59000

Protobothrops mucrosquamatus

-

heavy chain, consists of metalloproteinase, disintegrin and cysteine-rich domains

668852

59000

Daboia russelii

-

1 * 59000 (heavy chain contains a zinc-binding endopeptidase domain and a disintegrin) + 1 * 18000-21000 (heterogeneous light chain), Vipera russelli, SDS-PAGE

31350