3.4.24.57: O-sialoglycoprotein endopeptidase

This is an abbreviated version!
For detailed information about O-sialoglycoprotein endopeptidase, go to the full flat file.

Word Map on EC 3.4.24.57

3.4.24.57

o-sialoglycoproteins

pasteurella

haemolytica

neuraminidase

psgl-1

p-selectin

ligand-1

pasteurellosis

sialomucins

leukotoxin

drug development

medicine

Reaction

Hydrolysis of O-sialoglycoproteins; cleaves -Arg31-/-Asp- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated =

Synonyms

Gcp, Glycophorin A proteinase, Glycoprotease, Glycoproteinase, O-sialoglycoprotein endopeptidase, OSE, OSGE, PG0778, PG1724, Proteinase, glyco-, Sialoglycoprotease, Sialoglycoproteinase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.57 O-sialoglycoprotein endopeptidase

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Results	in table
1	Activating Compound
151	AA Sequence
2	Application
1	CAS Registry Number
1	Cloned(Commentary)
13	Disease/ Diagnostics
2	General Information
1	General Stability
3	Inhibitors
1	Ki Value [mM]
2	Localization
2	Metals/Ions
1	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
30	Organism
10	PDB ID
1	pH Optimum
1	pH Stability
1	Protein Variants
1	Purification (Commentary)
1	Reaction
1	Reaction Type
17	Reference
6	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
31	Substrates and Products (Substrate)
14	Synonyms
2	Temperature Optimum [°C]

Disease

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Disease on EC 3.4.24.57 - O-sialoglycoprotein endopeptidase

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Carcinoma

Cleavage of epitectin, a mucin-type sialoglycoprotein, from the surface of human laryngeal carcinoma cells by a glycoprotease from Pasteurella haemolytica.

8179312

Tk, a new colon tumor-associated antigen resulting from altered O-glycosylation.

11034094

Neoplasms

Cleavage of epitectin, a mucin-type sialoglycoprotein, from the surface of human laryngeal carcinoma cells by a glycoprotease from Pasteurella haemolytica.

8179312

Pasteurellosis, Pneumonic

Comparison of the recombinant and authentic forms of the Pasteurella haemolytica A1 glycoprotease.

9037761

Pneumonia

Cleavage of epitectin, a mucin-type sialoglycoprotein, from the surface of human laryngeal carcinoma cells by a glycoprotease from Pasteurella haemolytica.

8179312