3.4.24.56: insulysin

This is an abbreviated version!
For detailed information about insulysin, go to the full flat file.

Word Map on EC 3.4.24.56

3.4.24.56

alzheimer

neprilysin

abeta

hippocampus

dementia

mellitus

cerebral

morris

amyloid-beta

metalloprotease

maze

neuroprotective

amyloidogenic

tau

beta-amyloid

neurodegenerative

presenilin

endothelin-converting

senile

gamma-secretase

beta-protein

125i-insulin

abeta-degrading

hyperinsulinemia

metalloendopeptidase

bacitracin

beta-secretase

late-onset

amylin

microglia

medicine

adam10

non-amyloidogenic

glutathione-insulin

enzyme-1

b-chains

analysis

ad-like

anti-ide

exosite

beta-peptide

abeta1-40

Reaction

Degradation of insulin, glucagon and other polypeptides. No action on proteins =

Synonyms

ADE, amyloid degrading enzyme, cgd6_5510, EC 3.4.22.11, EC 3.4.99.10, EC 3.4.99.45, gamma-endorphin-generating enzyme, IDE, INS20-19, insulin degrading enzyme, Insulin protease, Insulin proteinase, Insulin-degrading enzyme, Insulin-degrading neutral proteinase, Insulin-glucagon protease, Insulin-specific protease, Insulinase, Insulysin, Metalloinsulinase, More, pitrilysin metallopeptidase 1, Pitrm1

ECTree

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.56 insulysin

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
73	Activating Compound
256	AA Sequence
17	Application
1	CAS Registry Number
60	Cloned(Commentary)
12	Crystallization (Commentary)
557	Disease/ Diagnostics
13	Expression
45	General Information
1	General Stability
58	IC50 Value
274	Inhibitors
10	kcat/KM [mM/s]
12	Ki Value [mM]
94	KM Value [mM]
88	Localization
64	Metals/Ions
44	Molecular Weight [Da]
138	Natural Substrates/ Products (Substrates)
338	Organism
135	PDB ID
29	pH Optimum
2	pH Range
3	pH Stability
2	Posttranslational Modification
94	Protein Variants
43	Purification (Commentary)
5	Reaction
1	Reaction Type
171	Reference
187	Source Tissue
16	Specific Activity [micromol/min/mg]
3	Storage Stability
416	Substrates and Products (Substrate)
40	Subunits
203	Synonyms
22	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
98	Turnover Number [1/s]

KI Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

KI Value on EC 3.4.24.56 - insulysin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

back to the top

Go to Ki Value Search

0.0037

ACSWWSIHLCG

pH and temperature not specified in the publication, substrate: insulin

0.000045 - 0.00015

ATP

show

0.0039

QSLPWCYPHCVT

pH and temperature not specified in the publication, substrate: insulin

0.0041

QSLPWCYPHCVT-NH2

pH and temperature not specified in the publication, substrate: insulin

0.007

VHWDFRQW-NH2

pH and temperature not specified in the publication, substrate: insulin

0.0008

VHWDFRQWWQPS

pH and temperature not specified in the publication, substrate: insulin

0.0013

VHWDFRQWWQPS-NH2

pH and temperature not specified in the publication, substrate: insulin

0.0015

WSPISGKFFQRF

pH and temperature not specified in the publication, substrate: insulin

0.0026

WSPISGKFFQRF-NH2

pH and temperature not specified in the publication, substrate: insulin

additional information

additional information

-

inhibition kinetics, overview

-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)