3.4.24.55: pitrilysin
This is an abbreviated version!
For detailed information about pitrilysin, go to the full flat file.
Word Map on EC 3.4.24.55
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3.4.24.55
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metalloprotease
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metalloendopeptidase
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presequence
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prep
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metallopeptidase
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zinc-binding
-
insulin-degrading
-
unstructured
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insulysin
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oligopeptidase
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insulinase
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nardilysin
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hxxeh
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peptidasome
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dibasic
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metalloendoprotease
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endoprotease
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b-chain
- 3.4.24.55
- metalloprotease
- metalloendopeptidase
- presequence
-
prep
- metallopeptidase
-
zinc-binding
-
insulin-degrading
- unstructured
- insulysin
-
oligopeptidase
- insulinase
- nardilysin
-
hxxeh
-
peptidasome
-
dibasic
- metalloendoprotease
- endoprotease
- b-chain
Reaction
Preferential cleavage of -Tyr16-/- Leu- and -Phe25-/- Tyr-bonds of oxidized insulin B chain. Also acts on other substrates of less than 7 kDa such as insulin and glucagon =
Synonyms
EC 3.4.99.44, Escherichia coli protease III, Pitrilysin, ppBH4, Protease Pi, Proteinase Pi, Proteinase, Escherichia coli metallo-, Pi, PTR
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Metals Ions
Metals Ions on EC 3.4.24.55 - pitrilysin
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Co2+
Mn2+
Zn2+
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most effective metal ion in reactivation after inhibition by chelating agent
Zn2+
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most effective metal ion in reactivation after inhibition by chelating agent
Zn2+
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contains 1.02-1.14 mol of zinc per mol of enzyme (depending on mutant)