3.4.24.52: trimerelysin I
This is an abbreviated version!
For detailed information about trimerelysin I, go to the full flat file.
Reaction
Cleavage of only two bonds His10-/-Leu and Ala14-/-Leu in the insulin B chain =
Synonyms
Hemorrhagic metalloproteinase HR1A, Hemorrhagic proteinase HR1A, HR1A, Metalloproteinase HR1A, metalloproteinase HR1b, Trimeresurus metalloendopeptidase I
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Reference
Reference on EC 3.4.24.52 - trimerelysin I
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Omori-Satoh, T.; Sadahiro, S.
Resolution of the major hemorrhagic component of Trimeresurus flavoviridis venom into two parts
Biochim. Biophys. Acta
580
392-404
1979
Protobothrops flavoviridis
Yamakawa, Y.; Omori-Satoh, T.
The sites of cleavage in oxidized insulin-B chain by a hemorrhagic protease derived from the venom of the habu (Trimeresurus flavoviridis)
Toxicon
26
227-231
1988
Protobothrops flavoviridis
Takeya, H.; Oda, K.; Miyata, T.; Omori-Satoh, T.; Iwanaga, S.
The complete amino acid sequence of the high molecular mass hemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis
J. Biol. Chem.
265
16068-16073
1990
Protobothrops flavoviridis
Takeya, H.; Nishida, S.; Nishino, N.; Makinose, Y.; Omori-Satoh, T.; Nikai, T.; Sugihara, H.; Iwanaga, S.
Primary structures of platelet aggregation inhibitors (disintegrins) autoproteolytically released from snake venom hemorrhagic metalloproteinases and new fluorogenic peptide substrates for these enzymes
J. Biochem.
113
473-483
1993
Protobothrops flavoviridis
Kawabata, S.; Iwanaga, S.
Trimerelysin I
Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press
1
702-703
2004
Protobothrops flavoviridis
-
Morine, N.; Matsuda, S.; Terada, K.; Eto, A.; Ishida, I.; Oku, H.
Neutralization of hemorrhagic snake venom metalloproteinase HR1a from Protobothrops flavoviridis by human monoclonal antibody
Toxicon
51
345-352
2008
Protobothrops flavoviridis
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