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3.4.24.47: horrilysin

This is an abbreviated version!
For detailed information about horrilysin, go to the full flat file.

Reaction

Cleavage of only the single bond Ala14-/-Leu in the insulin B chain, Ser12-/-Leu in the A chain, and Ile-/-Gly, Pro-/-Ala, and Ser-/-Trp in melittin =

Synonyms

Crotalus horridus metalloendopeptidase, Hemorrhagic proteinase IV, HP-IV, Proteinase, Crotalus horridus horridus venom hemorrhagic

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.47 horrilysin

Reference

Reference on EC 3.4.24.47 - horrilysin

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Civello, D.J.; Duong, H.L.; Geren, C.R.
Isolation and characterization of a hemorrhagic proteinase from timber rattlesnake venom
Biochemistry
22
749-755
1983
Crotalus horridus horridus
Manually annotated by BRENDA team
Civello, D.J.; Moran, J.B.; Geren, C.R.
Substrate specificity of a hemorrhagic proteinase from timber rattlesnake venom
Biochemistry
22
755-762
1983
Crotalus horridus horridus
Manually annotated by BRENDA team
Bjarnason, J.B.; Fox, J.W.
Horrilysin
Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press
1
681-682
2004
Crotalus horridus horridus
-
Manually annotated by BRENDA team