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3.4.24.47: horrilysin

This is an abbreviated version!
For detailed information about horrilysin, go to the full flat file.

Reaction

Cleavage of only the single bond Ala14-/-Leu in the insulin B chain, Ser12-/-Leu in the A chain, and Ile-/-Gly, Pro-/-Ala, and Ser-/-Trp in melittin =

Synonyms

Crotalus horridus metalloendopeptidase, Hemorrhagic proteinase IV, HP-IV, Proteinase, Crotalus horridus horridus venom hemorrhagic

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.47 horrilysin

Natural Substrates Products

Natural Substrates Products on EC 3.4.24.47 - horrilysin

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
-
hemorrhage inducing toxin
-
-
?