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3.4.24.47: horrilysin

This is an abbreviated version!
For detailed information about horrilysin, go to the full flat file.

Reaction

Cleavage of only the single bond Ala14-/-Leu in the insulin B chain, Ser12-/-Leu in the A chain, and Ile-/-Gly, Pro-/-Ala, and Ser-/-Trp in melittin =

Synonyms

Crotalus horridus metalloendopeptidase, Hemorrhagic proteinase IV, HP-IV, Proteinase, Crotalus horridus horridus venom hemorrhagic

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.47 horrilysin

Application

Application on EC 3.4.24.47 - horrilysin

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
medicine
-
horrilysin possesses hemorrhagic and lethal activities